Okamoto K, Morioka T
Department of Anesthesiology, Kumamoto University Medical School, Japan.
Resuscitation. 1990 Dec;20(3):253-62. doi: 10.1016/0300-9572(90)90008-3.
We examined the efficiency of continuous transtracheal O2 insufflation (TOI) as a method of ventilation during cardiopulmonary resuscitation (CPR) in a canine model. The tip of the insufflation catheter was placed 1 cm above the carina. The effects of TOI at flow rates of 0.2, 0.5, and 1.0 l/kg per min during and after CPR were examined in dogs with induced ventricular fibrillation. During CPR, adequate oxygenation and ventilation were maintained with TOI at flow rates of 0.5 and 1.0 l/kg per min, but not at 0.2 l/kg per min. After CPR, TOI was adequate to maintain oxygenation, but not ventilation. TOI alone did not prevent post-CPR hypercarbia in successfully resuscitated animals. Still, this study suggests that TOI might be useful as a temporary measure for emergency ventilation during CPR, especially in situations such as upper airway abnormalities, when mask ventilation or endotracheal intubation is not feasible.
我们在犬类模型中研究了持续经气管给氧(TOI)作为心肺复苏(CPR)期间一种通气方法的效率。给氧导管尖端置于隆突上方1厘米处。在诱发心室颤动的犬中,研究了心肺复苏期间及之后以每分钟0.2、0.5和1.0升/千克的流速进行经气管给氧的效果。在心肺复苏期间,以每分钟0.5和1.0升/千克的流速进行经气管给氧可维持充分的氧合和通气,但以每分钟0.2升/千克的流速则不能。心肺复苏后,经气管给氧足以维持氧合,但不能维持通气。单独使用经气管给氧并不能防止成功复苏动物出现心肺复苏后高碳酸血症。尽管如此,本研究表明,经气管给氧可能作为心肺复苏期间紧急通气的临时措施有用,特别是在上气道异常等面罩通气或气管插管不可行的情况下。