Kruse K M, Gust R, Grosse-Heitmeyer W
Medizinische Klinik, St.-Bonifatius-Hospital, Lingen, Ems.
Dtsch Med Wochenschr. 1992 Jan 31;117(5):167-71. doi: 10.1055/s-2008-1062294.
A 49-year-old man suddenly developed dyspnoea, sweating, fever (up to 38.5 degrees C), vertigo and angina. After emergency admittance to hospital the ECG showed 3 degrees A-V block, requiring temporary pacemaker insertion. The patient reported that a month before he had been bitten, probably by a tick. Serological tests demonstrated a recent Borrelia infection (rise of IgG antibody titre to 1:2048, IgM antibody titre to 1:128). Coronary angiography excluded any haemodynamically significant coronary heart disease as a cause of the conduction disorder. Myocardial biopsy showed changes pointing to a past myocarditis. This suggested Borrelia infection as the cause of the complete A-V block. Under treatment with broad-spectrum antibiotics for 15 days the fever subsided and the ECG became normal. Shortly before discharge, an elevated pulmonary wedge pressure on 150 W exercise indicated persistence of mild left-ventricular failure.
一名49岁男性突然出现呼吸困难、出汗、发热(体温高达38.5摄氏度)、眩晕和心绞痛。紧急入院后,心电图显示三度房室传导阻滞,需要插入临时起搏器。患者报告称,一个月前他可能被蜱虫叮咬过。血清学检测显示近期感染了伯氏疏螺旋体(IgG抗体滴度升至1:2048,IgM抗体滴度升至1:128)。冠状动脉造影排除了任何具有血流动力学意义的冠心病作为传导障碍的病因。心肌活检显示有既往心肌炎的改变。这表明伯氏疏螺旋体感染是完全性房室传导阻滞的病因。在使用广谱抗生素治疗15天后,发热消退,心电图恢复正常。出院前不久,150瓦运动时肺楔压升高表明轻度左心室衰竭持续存在。