Medley R S, DeLapp T D, Fisher D G
University of Alaska, Anchorage.
Heart Lung. 1992 Jan;21(1):12-7.
In this study we examined the relationship between cardiac output (CO) measurements obtained from the proximal injectate lumen and the proximal infusion lumen of a thermodilution pulmonary artery catheter. The research was predicated on the belief that a strongly significant relationship would provide the clinician with an alternative lumen for measuring CO. Twenty-one subjects were selected by using a nonprobability convenience sampling method. With ice temperature injectate, four injections were performed into one lumen followed by four injections into the alternate lumen. CO values were computed with installed data management physiologic monitors. A Pearson's Product-Moment Correlation Coefficient was calculated, and the result verified a strong positive correlation between CO values (r = 0.96, p = less than 0.0001). Results of a paired t test demonstrated no statistically significant differences between CO means. These findings lend direction for minimizing the potential risk of catheter contamination associated with the manipulation of intravenous lines containing vasoactive medications. It also may save time for the critical care clinician who is trying to balance tasks such as CO measurements and titration of vasoactive or inotropic medications.
在本研究中,我们检测了通过热稀释肺动脉导管的近端注射腔和近端输注腔测得的心输出量(CO)之间的关系。该研究基于这样一种信念,即一种显著的强相关性将为临床医生提供一个用于测量CO的替代腔。采用非概率便利抽样法选取了21名受试者。使用冰温注射液,先向一个腔进行4次注射,然后向另一个腔进行4次注射。通过安装的数据管理生理监测仪计算CO值。计算了皮尔逊积差相关系数,结果证实CO值之间存在强正相关(r = 0.96,p < 0.0001)。配对t检验结果显示CO均值之间无统计学显著差异。这些发现为将与含有血管活性药物的静脉输液管操作相关的导管污染潜在风险降至最低提供了指导。这也可能为试图平衡诸如CO测量和血管活性或强心药物滴定等任务的重症监护临床医生节省时间。