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肥胖女性肛门失禁的风险。

The risk of anal incontinence in obese women.

作者信息

Altman Daniel, Falconer Christian, Rossner Stephan, Melin Ingela

机构信息

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.

出版信息

Int Urogynecol J Pelvic Floor Dysfunct. 2007 Nov;18(11):1283-9. doi: 10.1007/s00192-007-0341-9. Epub 2007 Mar 14.

Abstract

The objectives of this study was to estimate the risk of anal incontinence in morbidly obese women and to identify risk factors associated with anal incontinence in an obese population sample. A case-control study based on the registry of a university hospital obesity unit. A consecutive sample of women with body mass index > or = 35 (obesity class II) was randomly matched by age, gender and residential county to control subjects using the computerised Register of the Total Population. Data were collected by a self-reported postal survey including detailed questions on medical and obstetrical history, obesity history, socioeconomic indices, life style factors and the validated Cleveland Clinic Incontinence Score. The questionnaire was returned by 131/179 (73%) of the cases and 453/892 (51%) of the control subjects. Compared to the control group, obese women reported a significantly increased defecation frequency (p < 0.001), inability to discriminate between flatus and faeces (p < 0.001) and flatus incontinence (p < 0.001). Compared with non-obese women, the adjusted odds ratio (OR) for flatus incontinence in morbidly obese women was 1.5 [95% confidence interval (CI) 1.1-4.1]. A history of obstetric sphincter injury was independently associated with an increased risk of flatus incontinence (OR, 4.3; 95% CI, 2.0-9.2) and incontinence of loose stools (OR, 6.6; 95% CI, 1.4-31.4). Other medical and life style interactions did not remain at significant levels in an adjusted multivariable analysis. Obese women are at increased risk for mild to moderate flatus incontinence.

摘要

本研究的目的是评估病态肥胖女性肛门失禁的风险,并确定肥胖人群样本中与肛门失禁相关的风险因素。这是一项基于大学医院肥胖科登记处的病例对照研究。将体重指数≥35(肥胖II级)的女性连续样本,按照年龄、性别和居住县,使用总人口计算机登记册与对照对象进行随机匹配。通过自我报告的邮政调查收集数据,包括有关医疗和产科病史、肥胖病史、社会经济指标、生活方式因素以及经过验证的克利夫兰诊所失禁评分的详细问题。131/179(73%)的病例和453/892(51%)的对照对象返回了问卷。与对照组相比,肥胖女性报告排便频率显著增加(p<0.001)、无法区分屁和粪便(p<0.001)以及屁失禁(p<0.001)。与非肥胖女性相比,病态肥胖女性屁失禁的调整优势比(OR)为1.5[95%置信区间(CI)1.1 - 4.1]。产科括约肌损伤史与屁失禁风险增加(OR,4.3;95%CI,2.0 - 9.2)和稀便失禁(OR,6.6;95%CI,1.4 - 31.4)独立相关。在调整后的多变量分析中,其他医疗和生活方式的相互作用未保持在显著水平。肥胖女性发生轻度至中度屁失禁的风险增加。

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