Mohamed Samar S, Salama Magdy M A
E&CE Dept., University of Waterloo, Waterloo, Ontario, Canada.
Biomed Eng Online. 2007 Mar 15;6:10. doi: 10.1186/1475-925X-6-10.
Identifying the location and the volume of the prostate is important for ultrasound-guided prostate brachytherapy. Prostate volume is also important for prostate cancer diagnosis. Manual outlining of the prostate border is able to determine the prostate volume accurately, however, it is time consuming and tedious. Therefore, a number of investigations have been devoted to designing algorithms that are suitable for segmenting the prostate boundary in ultrasound images. The most popular method is the deformable model (snakes), a method that involves designing an energy function and then optimizing this function. The snakes algorithm usually requires either an initial contour or some points on the prostate boundary to be estimated close enough to the original boundary which is considered a drawback to this powerful method.
The proposed spectral clustering segmentation algorithm is built on a totally different foundation that doesn't involve any function design or optimization. It also doesn't need any contour or any points on the boundary to be estimated. The proposed algorithm depends mainly on graph theory techniques.
Spectral clustering is used in this paper for both prostate gland segmentation from the background and internal gland segmentation. The obtained segmented images were compared to the expert radiologist segmented images. The proposed algorithm obtained excellent gland segmentation results with 93% average overlap areas. It is also able to internally segment the gland where the segmentation showed consistency with the cancerous regions identified by the expert radiologist.
The proposed spectral clustering segmentation algorithm obtained fast excellent estimates that can give rough prostate volume and location as well as internal gland segmentation without any user interaction.
确定前列腺的位置和体积对于超声引导下的前列腺近距离放射治疗很重要。前列腺体积对于前列腺癌的诊断也很重要。手动勾勒前列腺边界能够准确确定前列腺体积,然而,这既耗时又繁琐。因此,许多研究致力于设计适用于在超声图像中分割前列腺边界的算法。最流行的方法是可变形模型(蛇形模型),该方法涉及设计一个能量函数,然后对该函数进行优化。蛇形算法通常需要一个初始轮廓或前列腺边界上的一些点,且这些点要足够接近原始边界,这被认为是这种强大方法的一个缺点。
所提出的谱聚类分割算法建立在一个完全不同的基础上,不涉及任何函数设计或优化。它也不需要估计任何轮廓或边界上的任何点。所提出的算法主要依赖于图论技术。
本文将谱聚类用于从背景中分割前列腺以及内部腺体分割。将获得的分割图像与专家放射科医生分割的图像进行比较。所提出的算法获得了出色的腺体分割结果,平均重叠面积为93%。它还能够对腺体进行内部分割,其分割结果与专家放射科医生确定的癌性区域一致。
所提出的谱聚类分割算法获得了快速且出色的估计结果,无需任何用户交互就能给出大致的前列腺体积和位置以及内部腺体分割。