[墨西哥利什曼原虫（利什曼原虫属）在哥伦比亚安蒂奥基亚省西北部戈麦斯普拉塔市圣马蒂亚斯村]
[Leishmania (leishmania) mexicana in the village of San Matias, municipality of Gomez Plata, North West of Antioquia, Colombia].
作者信息
Sierra Diana, Ochoa Marcela, Calle José Ignacio, García Gisela, Colorado Diana, Vélez Iván Darío
机构信息
Programa de Estudio y Control de Enfermedades Tropicales, Universidad de Antioquia, Medellín, Colombia.
出版信息
Biomedica. 2006 Oct;26 Suppl 1:232-5.
INTRODUCTION
Leishmaniasis is found in natural foci of infection where both sand fly vectors and mammalian reservoirs of Leishmania are present.
OBJECTIVE
To report for the first time the presence of Leishmania (Leishmania) mexicana Biagi, 1953, in the village of San Matías, municipality of Gomez Plata, Department of Antioquia.
MATERIALS AND METHODS
The parasite was isolated from a patient with localized cutaneous leishmaniasis and was identified by the immunofluorescence technique using specific monoclonal antibodies against L. mexicana species and isoenzyme electrophoresis.
RESULTS AND CONCLUSION
The isoenzymatic profiles of the reference strains L. (L.) mexicana (MNCY/BZ/62/M379) and L. (L.) mexicana (MHOM/BE/82/BEL21) were similar to that of the isolate recovered from the patient, allowing us to classify it as L. (L.) mexicana.
引言
利什曼病存在于感染的自然疫源地，那里同时存在白蛉传播媒介和利什曼原虫的哺乳动物宿主。
目的
首次报告在安蒂奥基亚省戈麦斯普拉塔市圣马蒂亚斯村发现1953年的墨西哥利什曼原虫（利什曼原虫属）。
材料与方法
从一名患有局限性皮肤利什曼病的患者身上分离出寄生虫，并使用针对墨西哥利什曼原虫物种的特异性单克隆抗体通过免疫荧光技术和同工酶电泳进行鉴定。
结果与结论
参考菌株墨西哥利什曼原虫（MNCY/BZ/62/M379）和墨西哥利什曼原虫（MHOM/BE/82/BEL21）的同工酶谱与从患者身上分离出的菌株相似，这使我们能够将其归类为墨西哥利什曼原虫。
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