Laboratorio de Biomedicina Molecular, Facultad de Ciencias Quimico Biologicas, Universidad Autonoma de Sinaloa, Culiacán, Mexico.
Vector Borne Zoonotic Dis. 2012 Jan;12(1):78-80. doi: 10.1089/vbz.2011.0688. Epub 2011 Sep 16.
Leishmaniasis has been considered endemic in Sinaloa, Mexico, since 1994. Despite that Leishmania mexicana is the main etiological agent of cutaneous leishmaniasis (CL) in other regions of Mexico, the species causing CL in patients from Sinaloa state has not been previously established, although Leishmania braziliensis has been found in the neighboring southern state, Nayarit. L. braziliensis is also associated with mucocutaneous leishmaniasis, which is a more complicated clinical variant. Due to the implications on individual and public health, the objective of this report was to identify the Leishmania species present in Sinaloa, Mexico. Using the first internal transcribed spacer (ITS-1) polymerase chain reaction-restriction fragment length polymorphism, we identified L. mexicana in a CL patient from Sinaloa and confirmed the extended distribution of this parasite in Mexico.
利什曼病自 1994 年以来一直被认为在墨西哥锡那罗亚州流行。尽管在墨西哥其他地区，墨西哥利什曼原虫是皮肤利什曼病（CL）的主要病因，但此前尚未确定导致锡那罗亚州患者 CL 的物种，尽管在邻国纳亚里特州发现了利什曼巴西利什曼原虫。利什曼巴西利什曼原虫也与黏膜皮肤利什曼病有关，这是一种更复杂的临床变异。由于对个人和公共卫生的影响，本报告的目的是确定墨西哥锡那罗亚州存在的利什曼虫种。使用第一内部转录间隔区（ITS-1）聚合酶链反应-限制性片段长度多态性，我们在一名来自锡那罗亚州的 CL 患者中鉴定出了墨西哥利什曼原虫，并证实了这种寄生虫在墨西哥的广泛分布。
