复发性转移性宫颈癌挽救化疗后出现无疾病证据的意外长期生存：病例系列
Unexpected long-term survival without evidence of disease after salvage chemotherapy for recurrent metastatic cervical cancer: a case series.
作者信息
Khoury-Collado Fady, Bowes Robert J, Jhamb Namita, Aghajanian Carol, Abu-Rustum Nadeem R
机构信息
Department of Obstetrics and Gynecology, Lutheran Medical Center, Brooklyn, NY 11220, USA.
出版信息
Gynecol Oncol. 2007 Jun;105(3):823-5. doi: 10.1016/j.ygyno.2007.02.009. Epub 2007 Mar 23.
BACKGROUND
The prognosis of recurrent metastatic cervical cancer is extremely poor. Platinum-based palliative chemotherapy constitutes the mainstay of treatment. Cure is extremely rare.
CASE
We present 3 cases of recurrent metastatic cervical cancer in which the patients remain disease-free many years after completing salvage chemotherapy and surgery. The patients remain with no evidence of disease at 6, 7, and 13 years, respectively, following recurrence.
CONCLUSION
In rare cases, an unexpected complete clinical remission and long-term survival without evidence of disease may be achieved in patients with recurrent metastatic cervical cancer treated with multimodal therapy.
背景
复发性转移性宫颈癌的预后极差。铂类姑息化疗是主要的治疗方法。治愈极为罕见。
病例
我们报告3例复发性转移性宫颈癌病例，这些患者在完成挽救性化疗和手术后多年无疾病复发。复发后，患者分别在6年、7年和13年时仍无疾病证据。
结论
在罕见情况下，接受多模式治疗的复发性转移性宫颈癌患者可能会出现意外的完全临床缓解且长期无疾病证据生存。
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