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通过计算机断层扫描和磁共振成像对急性胰腺炎的严重程度及预后进行分期——一项对比研究

Staging of severity and prognosis of acute pancreatitis by computed tomography and magnetic resonance imaging-a comparative study.

作者信息

Arvanitakis M, Koustiani G, Gantzarou A, Grollios G, Tsitouridis I, Haritandi-Kouridou A, Dimitriadis A, Arvanitakis C

机构信息

Department of Gastroenterology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

出版信息

Dig Liver Dis. 2007 May;39(5):473-82. doi: 10.1016/j.dld.2007.01.015. Epub 2007 Mar 23.

DOI:10.1016/j.dld.2007.01.015
PMID:17363349
Abstract

BACKGROUND

Determination of severity of acute pancreatitis is important to determine prognosis.

AIMS

(1) the staging of acute pancreatitis by computed tomography and magnetic resonance imaging, (2) the correlation of computed tomography and magnetic resonance severity indices and 3) the correlation of magnetic resonance severity index with C-reactive protein, Ranson score, duration of hospitalization and clinical outcome.

PATIENTS

Thirty-five patients (median age: 64 (27-89)) were studied. Twenty-two patients had biliary acute pancreatitis.

METHODS

The following examinations were conducted: (1) computed tomography 48 h, 7 and 30 days after admission, (2) magnetic resonance imaging 7 and 30 days after admission, (3) C-reactive protein and 4) Ranson score. Clinical outcome was determined on a scale 0-3 (0: remission, 1: local complications, 2: systemic complications, 3: death).

RESULTS

Six of 35 patients (17%) had necrotizing acute pancreatitis. Fifteen of 35 patients (43%) had severe acute pancreatitis according to Ranson criteria. A significant correlation was noted between magnetic resonance severity index and C-reactive protein (r=0.419, p<0.005), Ranson score (r=0.431, p<0.05), duration of hospitalization (r=0.497, p<0.01) and clinical outcome (r=0.420, p<0.05). Comparison of the imaging methods showed a significant correlation between magnetic resonance severity index and computed tomography severity index (r=0.887, p<0.01).

CONCLUSION

Magnetic resonance imaging is of comparable diagnostic and prognostic value with computed tomography in the staging of acute pancreatitis.

摘要

背景

确定急性胰腺炎的严重程度对于判断预后很重要。

目的

(1)通过计算机断层扫描和磁共振成像对急性胰腺炎进行分期,(2)计算机断层扫描和磁共振严重程度指数的相关性,以及(3)磁共振严重程度指数与C反应蛋白、兰森评分、住院时间和临床结局的相关性。

患者

研究了35例患者(中位年龄:64岁(27 - 89岁))。22例患者患有胆源性急性胰腺炎。

方法

进行了以下检查:(1)入院后48小时、7天和30天的计算机断层扫描,(2)入院后7天和30天的磁共振成像,(3)C反应蛋白,以及(4)兰森评分。临床结局按0 - 3级评定(0:缓解,1:局部并发症,2:全身并发症,3:死亡)。

结果

35例患者中有6例(17%)患有坏死性急性胰腺炎。根据兰森标准,35例患者中有15例(43%)患有重症急性胰腺炎。磁共振严重程度指数与C反应蛋白(r = 0.419,p < 0.005)、兰森评分(r = 0.431,p < 0.05)、住院时间(r = 0.497,p < 0.01)和临床结局(r = 0.420,p < 0.05)之间存在显著相关性。成像方法的比较显示磁共振严重程度指数与计算机断层扫描严重程度指数之间存在显著相关性(r = 0.887,p < 0.01)。

结论

在急性胰腺炎分期方面,磁共振成像与计算机断层扫描具有相当的诊断和预后价值。

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