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面向社区的风湿性疾病控制项目关于发展中国家健康状况测量与监测数据收集的建议。

Recommendations from the Community Oriented Program for Control of Rheumatic Disease for data collection for the measurement and monitoring of health in developing countries.

作者信息

Darmawan John

机构信息

WHO Collaborating Center, Community-based Epidemiology, Prevention, and Treatment of Rheumatic Disease, Indonesia Rheumatic Center, Jalan Seroja Dalam 7, Semarang-Jakarta, 50136, Indonesia.

出版信息

Clin Rheumatol. 2007 Jun;26(6):853-7. doi: 10.1007/s10067-007-0553-x. Epub 2007 Mar 16.

Abstract

The history of the World Health Organization-International League of Associations for Rheumatology Community Oriented Program for Control of Rheumatic Disease (COPCORD) for developing countries is described. Due to lack of funding and manpower, the COPCORD concept is designed in three stages for execution. Stage I is a community-based epidemiology of rheumatism in three phases by rheumatologist but non-epidemiologist to save time, money, and costs. Stage II is education of treatment of rheumatism. Stage III is the identification of environmental and genetic risk factors of musculoskeletal disorders to prevent or minimize rheumatism. Since 1980, COPCORD has collected valid community-based epidemiological data, which are published in 42 papers since 1985 in various international rheumatology journals. The publications were from 19 developing countries in the Asia Pacific region, South America, Europe, and Africa. Stage II education is deemed to be more appropriate handled by allied rheumatology health professionals. Low back pain, osteoarthritis, osteoporosis, and rheumatoid arthritis (RA) are the priority. The projected prevalence of RA in >4 billion people in countries of the South are between 8 and 12 million patients and urgently require adequate control. After 5-15 years, the consequences of RA are disability, reduced productivity, loss of career and income, lowered quality of life, and early mortality notwithstanding existing therapy. The application of the Biologic DMARDs in RA in the Third World for reasons of treatment costs from $15,000 to $25,000 per patient per year is not feasible. The majority of the Third World population has an income of less than US$1.00 per day to less than US$2,000.00 per capita. The COPCORD has designed and applied successfully the step-down bridge guidelines of intravenous and oral combination of five generic immunosuppressants in prospective observational studies of rheumatoid factor positive RA in Indonesia, China, and Iran. Recommendations of the COPCORD stages are submitted.

摘要

本文描述了世界卫生组织-国际风湿病协会联盟面向发展中国家的风湿病控制社区导向项目(COPCORD)的历史。由于缺乏资金和人力,COPCORD概念分三个阶段实施。第一阶段是由风湿病学家而非流行病学家分三个阶段进行基于社区的风湿病流行病学调查,以节省时间、资金和成本。第二阶段是风湿病治疗教育。第三阶段是识别肌肉骨骼疾病的环境和遗传风险因素,以预防或减少风湿病。自1980年以来,COPCORD收集了有效的基于社区的流行病学数据,自1985年起在各种国际风湿病学杂志上发表了42篇论文。这些出版物来自亚太地区、南美洲、欧洲和非洲的19个发展中国家。第二阶段的教育被认为由联合风湿病健康专业人员处理更为合适。腰痛、骨关节炎、骨质疏松症和类风湿关节炎(RA)是重点。预计南方国家40多亿人口中RA的患病率在800万至1200万患者之间,迫切需要进行充分控制。5至15年后,尽管有现有治疗方法,RA的后果仍是残疾、生产力下降、职业和收入丧失、生活质量降低以及过早死亡。由于每名患者每年治疗费用从15000美元到25000美元不等,生物性改善病情抗风湿药在第三世界用于RA治疗并不可行。第三世界的大多数人口日收入低于1美元,人均收入低于2000美元。COPCORD在前瞻性观察研究中,成功设计并应用了静脉和口服联合使用五种通用免疫抑制剂的逐步递减桥梁指南,用于印度尼西亚、中国和伊朗类风湿因子阳性RA的研究。文中提交了COPCORD各阶段的建议。

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