Mostafa Badr E, Shafik Amr G, Fawaz Samia
Faculty of Medicine, Ain-Shams University, Cairo, Egypt.
Acta Otolaryngol. 2007 Feb;127(2):175-9. doi: 10.1080/00016480600743773.
Autofluorescent endoscopy (AFE) combined with microlaryngoscopy (MLS) gives a more accurate diagnosis of laryngeal pathology and can be further refined to minimize the need for MLS under general anaesthesia.
The aim of the present study was to evaluate the diagnostic potential and limitations of autofluorescent flexible laryngoscopy in comparison to MLS.
We examined 40 patients using the Pentax SAFE 1000 system. All patients then underwent direct MLS and biopsy under general anaesthesia. Biopsies were taken from areas that were visually suspicious and then from areas that showed disturbed autofluorescent signals.
The overall sensitivity of AFE for various pathologies was 90.625%, while the sensitivity of MLS was 75%. Combining the findings of AFL and MLS we had a 100% diagnostic yield.
自体荧光内镜检查（AFE）联合显微喉镜检查（MLS）能更准确地诊断喉部病变，并且可以进一步优化以尽量减少在全身麻醉下进行MLS的必要性。
本研究的目的是评估与MLS相比，自体荧光软性喉镜检查的诊断潜力和局限性。
我们使用宾得SAFE 1000系统检查了40例患者。所有患者随后均在全身麻醉下接受直接MLS和活检。从视觉上可疑的区域以及显示自体荧光信号受干扰的区域进行活检。
AFE对各种病变的总体敏感性为90.625%，而MLS的敏感性为75%。结合AFL和MLS的检查结果，我们的诊断率达到了100%。
