Schellhammer P F, Jordan G H, Robey E L, Spaulding J T
Department of Urology, Eastern Virginia Medical School, Norfolk.
Urol Clin North Am. 1992 Feb;19(1):131-42.
Premalignant lesions of the penis include cutaneous horn, balanitis xerotica obliterans, and leukoplakia. The true incidence of progression of each of these to squamous-cell carcinoma is unknown. Bowenoid papulosis, erythroplasia of Queyrat, and Bowen's disease are histologically identical to in situ carcinoma. Although the first is consistently benign, the latter two regularly evolve into invasive cancer. Malignant scrotal lesions include squamous-cell carcinoma, liposarcoma, leiomyosarcoma, basal-cell carcinoma, extramammary Paget's disease, erythroplasia of Queyrat, malignant melanoma, and metastases. Hemangioma can be confused with carcinoma.
阴茎的癌前病变包括皮肤角、闭塞性干燥性龟头炎和白斑。这些病变发展为鳞状细胞癌的真实发生率尚不清楚。鲍温样丘疹病、凯腊增殖性红斑和鲍恩病在组织学上与原位癌相同。虽然前者一直是良性的,但后两者通常会发展为浸润性癌。阴囊恶性病变包括鳞状细胞癌、脂肪肉瘤、平滑肌肉瘤、基底细胞癌、乳房外佩吉特病、凯腊增殖性红斑、恶性黑色素瘤和转移瘤。血管瘤可能会与癌混淆。