阴茎角：一例经口服阿维A成功治疗的假上皮瘤样、角化性和云母状龟头炎罕见病例
Penile Horn: A Rare Presentation of Pseudoepitheliomatous, Keratotic, and Micaceous Balanitis Successfully Treated with Oral Acitretin.
作者信息
Sirka Chandra Sekhar, Sahu Kananbala, Pradhan Swetalina, Naik Subhasini
机构信息
Department of Dermatology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Department of Pathology, S.C.B. Medical College, Cuttack, Odisha, India.
出版信息
Indian Dermatol Online J. 2019 Jul-Aug;10(4):460-462. doi: 10.4103/idoj.IDOJ_305_18.
Glans penis is an unusual site for horn. Only few cases are reported worldwide in English literature. Pseudoepitheliomatous, keratotic, and micaceous balanitis (PKMB) is a pyodermatitis with pseudoepitheliomatous response to chronic inflammation or infection. Rarely it can develop a horn. There is one case report of PKMB presenting as penile horn and one case with nail-like presentation in the literature. Mode of treatment of PKMB with horn ranged from topical 5-fluorouracil, electrosurgery, and cryosurgery to excision. Use of oral acitretin in PKMB or penile horn is unknown. We are reporting a 60-year-old circumcised male who presented with a penile horn. Histology was suggestive of PKMB. Treatment with topical 5-flurouracil did not work. He was successfully treated with oral acitretin.
阴茎头是角质形成的罕见部位。英文文献中全球仅报道了少数病例。假上皮瘤样、角化性和云母状龟头炎（PKMB）是一种对慢性炎症或感染有假上皮瘤样反应的脓皮病。它很少会形成角质。文献中有一例PKMB表现为阴茎角的病例报告，还有一例呈指甲样表现的病例。伴有角质的PKMB的治疗方式包括局部使用5-氟尿嘧啶、电外科手术、冷冻手术及切除。PKMB或阴茎角使用口服阿维A的情况尚不清楚。我们报告了一名60岁行包皮环切术的男性，其出现阴茎角。组织学检查提示为PKMB。局部使用5-氟尿嘧啶治疗无效。他口服阿维A成功治愈。
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