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阴茎角:一例经口服阿维A成功治疗的假上皮瘤样、角化性和云母状龟头炎罕见病例

Penile Horn: A Rare Presentation of Pseudoepitheliomatous, Keratotic, and Micaceous Balanitis Successfully Treated with Oral Acitretin.

作者信息

Sirka Chandra Sekhar, Sahu Kananbala, Pradhan Swetalina, Naik Subhasini

机构信息

Department of Dermatology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Department of Pathology, S.C.B. Medical College, Cuttack, Odisha, India.

出版信息

Indian Dermatol Online J. 2019 Jul-Aug;10(4):460-462. doi: 10.4103/idoj.IDOJ_305_18.

DOI:10.4103/idoj.IDOJ_305_18
PMID:31334071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6615373/
Abstract

Glans penis is an unusual site for horn. Only few cases are reported worldwide in English literature. Pseudoepitheliomatous, keratotic, and micaceous balanitis (PKMB) is a pyodermatitis with pseudoepitheliomatous response to chronic inflammation or infection. Rarely it can develop a horn. There is one case report of PKMB presenting as penile horn and one case with nail-like presentation in the literature. Mode of treatment of PKMB with horn ranged from topical 5-fluorouracil, electrosurgery, and cryosurgery to excision. Use of oral acitretin in PKMB or penile horn is unknown. We are reporting a 60-year-old circumcised male who presented with a penile horn. Histology was suggestive of PKMB. Treatment with topical 5-flurouracil did not work. He was successfully treated with oral acitretin.

摘要

阴茎头是角质形成的罕见部位。英文文献中全球仅报道了少数病例。假上皮瘤样、角化性和云母状龟头炎(PKMB)是一种对慢性炎症或感染有假上皮瘤样反应的脓皮病。它很少会形成角质。文献中有一例PKMB表现为阴茎角的病例报告,还有一例呈指甲样表现的病例。伴有角质的PKMB的治疗方式包括局部使用5-氟尿嘧啶、电外科手术、冷冻手术及切除。PKMB或阴茎角使用口服阿维A的情况尚不清楚。我们报告了一名60岁行包皮环切术的男性,其出现阴茎角。组织学检查提示为PKMB。局部使用5-氟尿嘧啶治疗无效。他口服阿维A成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92a/6615373/92680d6fd724/IDOJ-10-460-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92a/6615373/e33f2625043d/IDOJ-10-460-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92a/6615373/92680d6fd724/IDOJ-10-460-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92a/6615373/e33f2625043d/IDOJ-10-460-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b92a/6615373/92680d6fd724/IDOJ-10-460-g003.jpg

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本文引用的文献

1
Efficacy of acitretin for porokeratosis in a child with chronic cutaneous graft versus host disease.阿维A治疗一名患有慢性皮肤移植物抗宿主病儿童的斑状汗孔角化症的疗效。
Pediatr Dermatol. 2013 Jan-Feb;30(1):148-50. doi: 10.1111/j.1525-1470.2011.01610.x. Epub 2011 Nov 16.
2
Pseudoepitheliomatous, keratotic and micaceous balanitis producing nail-like lesion on the glans penis.阴茎头出现类似指甲样损害的假上皮瘤样、角化性和云母状龟头炎。
Indian J Dermatol Venereol Leprol. 1999 Mar-Apr;65(2):75-7.
3
Pseudoepitheliomatous, keratotic, and micaceous balanitis presenting as cutaneous horn in an adult male.
皮肤病学中的“假性肿瘤”
Indian Dermatol Online J. 2022 Mar 3;13(2):294-301. doi: 10.4103/idoj.idoj_226_21. eCollection 2022 Mar-Apr.
表现为成人男性皮肤角化物的假上皮瘤样、角化和云母状龟头炎。
Indian J Dermatol Venereol Leprol. 2010 Sep-Oct;76(5):547-9. doi: 10.4103/0378-6323.69087.
4
Severe exacerbation of multiple self-healing squamous epithelioma (Ferguson-Smith disease) with radiotherapy, which was successfully treated with acitretin.放射性治疗后多发自愈性鳞状上皮瘤(Ferguson-Smith 病)重度恶化,阿维 A 酯治疗有效。
Clin Exp Dermatol. 2010 Jun;35(4):e100-2. doi: 10.1111/j.1365-2230.2009.03668.x. Epub 2009 Oct 23.
5
Pseudoepitheliomatous, keratotic, and micaceous balanitis: case report and review of the literature.假上皮瘤样、角化性和云母状龟头炎:病例报告及文献复习
Dermatol Nurs. 2008 Apr;20(2):117-20.
6
Treatment of epidermodysplasia verruciformis with a combination of acitretin and interferon alfa-2a.阿维A联合干扰素α-2a治疗疣状表皮发育不良
J Am Acad Dermatol. 2001 Aug;45(2):296-9. doi: 10.1067/mjd.2001.114575.
7
Cutaneous horn of glans penis.阴茎头皮肤角
Sex Transm Infect. 1998 Dec;74(6):456-7.
8
Xeroderma pigmentosum variant: 5 years of tumour suppression by etretinate.着色性干皮病变异型:依曲替酯5年的肿瘤抑制作用
J R Soc Med. 1993 Jun;86(6):355-6. doi: 10.1177/014107689308600615.
9
Pseudoepitheliomatous, keratotic, and micaceous balanitis.假上皮瘤样、角化性和云母状龟头炎。
Arch Dermatol. 1981 Jul;117(7):435-7.
10
Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells.维生素A及其类似物(类视黄醇)对正常细胞和肿瘤细胞的作用。
Biochim Biophys Acta. 1980 Mar 12;605(1):33-91. doi: 10.1016/0304-419x(80)90021-9.