柠檬酸在原发性甲状旁腺功能亢进合并肾石症中的作用。
Role of citric acid in primary hyperparathyroidism with renal lithiasis.
作者信息
Alvarez-Arroyo M V, Traba M L, Rapado A, de la Piedra C
机构信息
Lab. de la Unidad Metabólica, Fundación Jiménez Diaz, Madrid, Spain.
出版信息
Urol Res. 1992;20(1):88-90. doi: 10.1007/BF00294345.
PMID:1736494
Abstract
Nephrolithiasis is presented in 18-40% of patients with primary hyperparathyroidism. Our work suggests that citrate, an inhibitor of calcium salts, could be involved in the presence of renal lithiasis because hyperparathyroid stone formers show less citrate elimination than nonstone formers.
摘要
18% - 40%的原发性甲状旁腺功能亢进患者会出现肾结石。我们的研究表明，柠檬酸盐作为钙盐的抑制剂，可能与肾结石的形成有关，因为甲状旁腺功能亢进的结石形成者比非结石形成者的柠檬酸盐排泄更少。
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