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胃旁路术后韦尼克综合征导致的视力丧失

Visual loss due to Wernicke syndrome following gastric bypass.

作者信息

Longmuir Reid, Lee Andrew G, Rouleau Jacinthe

机构信息

The University of Iowa Hospitals and Clinics, Iowa City, IA, USA.

出版信息

Semin Ophthalmol. 2007 Jan-Mar;22(1):13-9. doi: 10.1080/08820530601182733.

Abstract

PURPOSE

To report a case of Wernicke encephalopathy after gastric bypass surgery resulting in vision loss, ophthalmoplegia, and ataxia, all of which reversed with a single dose of IV thiamine.

METHODS

Observational case report.

RESULTS

A 34-year-old woman presented with decreased vision and intermittent diplopia after gastric bypass surgery. She was found to have bilateral limitation of horizontal gaze, decreased vision with bilateral central scotoma and mild disc edema OU. Her cranial magnetic resonance imaging (MRI) was normal. A presumptive diagnosis of Wernicke encephalopathy was made. The patient was admitted, and a single dose of IV thiamine reversed the ophthalmoplegia and vision loss within 24 hours.

CONCLUSION

Wernicke encephalopathy should be considered in patients with vision loss after gastric bypass surgery. The classic triad of confusion, ataxia, and ophthalmoplegia may not be present and, although uncommon, the findings of optic disc edema and vision loss should not deter the clinician from making the diagnosis. Replacement thiamine if given promptly may rapidly reverse the findings.

摘要

目的

报告1例胃旁路手术后发生韦尼克脑病的病例,该病例出现视力丧失、眼肌麻痹和共济失调,所有这些症状在静脉注射单剂量硫胺素后均得到缓解。

方法

观察性病例报告。

结果

一名34岁女性在胃旁路手术后出现视力下降和间歇性复视。检查发现她存在双侧水平凝视受限、视力下降伴双侧中心暗点以及双眼轻度视盘水肿。她的头颅磁共振成像(MRI)正常。作出了韦尼克脑病的初步诊断。患者入院后,静脉注射单剂量硫胺素在24小时内逆转了眼肌麻痹和视力丧失。

结论

胃旁路手术后出现视力丧失的患者应考虑韦尼克脑病。可能不存在经典的意识模糊、共济失调和眼肌麻痹三联征,尽管不常见,但视盘水肿和视力丧失的表现不应妨碍临床医生作出诊断。如果及时给予补充硫胺素,可能会迅速逆转这些表现。

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