Kulkarni Sonalee, Lee Andrew G, Holstein Sarah A, Warner Judith E A
Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242-1091, USA.
Surv Ophthalmol. 2005 Jul-Aug;50(4):389-93. doi: 10.1016/j.survophthal.2005.04.005.
Wernicke encephalopathy consists of a triad of ophthalmoplegia, ataxia, and altered mental status. It is caused by thiamine deficiency and although it is commonly seen in alcoholics, patients undergoing gastric bypass surgery for morbid obesity could be a new group of patients to watch for. Florid papilloedema and optic neuropathy are not commonly seen but are still consistent with the diagnosis of Wernicke encephalopathy. The most striking feature remains the dramatic recovery after replacement of thiamine.
韦尼克脑病由眼肌麻痹、共济失调和精神状态改变三联征组成。它由硫胺素缺乏引起，虽然常见于酗酒者，但接受胃旁路手术治疗病态肥胖的患者可能是另一类需要关注的患者群体。明显的视乳头水肿和视神经病变并不常见，但仍符合韦尼克脑病的诊断。最显著的特征仍然是补充硫胺素后病情戏剧性的恢复。
