Halkiadakis Ioannis, Iliaki Olga, Kalyvianaki Maria I, Tsilimbaris Miltiadis K
University Eye Clinic of Heraklion, Crete, Greece.
Semin Ophthalmol. 2007 Jan-Mar;22(1):55-7. doi: 10.1080/08820530601182709.
In order to evaluate the role of botulinum toxin induced ptosis as an occlusion method to treat unilateral deep strabismic amblyopia in two uncooperative children, we injected 0.2 ml of diluted botulinum toxin in the levator palpaebrae; low sedation was necessary in one of the two children. In both cases a marked ptosis was achieved, which lasted about four weeks and then gradually resolved completely. The visual acuity of the ablyopic eye increased in both children, making patching easy thereafter. One child developed amblyopia in the injected eye, which was handled successfully using part-time occlusion. No other side effects were noted. Whether this new method could be a simple, safe and effective alternative method of occlusion for the treatment of deep amblyopia in uncooperative children needs to be proven with a larger series of children.
为了评估肉毒杆菌毒素诱导上睑下垂作为一种遮盖方法在治疗两名不合作儿童的单侧重度斜视性弱视中的作用，我们在提上睑肌中注射了0.2毫升稀释的肉毒杆菌毒素；两名儿童中有一名需要轻度镇静。在两例中均实现了明显的上睑下垂，持续约四周，然后逐渐完全消退。两名儿童弱视眼的视力均提高，此后便于进行遮盖。一名儿童在注射眼发生了弱视，通过部分时间遮盖成功处理。未观察到其他副作用。这种新方法是否可能成为治疗不合作儿童重度弱视的一种简单、安全且有效的替代遮盖方法，尚需通过更多儿童病例加以证实。
