Abu-Ain Mohammad S, Watts Patrick
Department of Special Surgeries, Faculty of Medicine, The Hashemite University, Zarqa, Jordan.
Department of Ophthalmology, University Hospital of Wales, Cardiff, Wales.
Saudi J Ophthalmol. 2022 Nov 22;37(1):6-9. doi: 10.4103/sjopt.sjopt_25_21. eCollection 2023 Jan-Mar.
The purpose of this study was to evaluate the usefulness and assess the risks associated with occlusive contact lenses (OCLs) use to treat refractory amblyopia in children who failed the conventional amblyopia treatment with patching and atropine penalization.
This was a retrospective case series of all children treated with an OCL in the sound eye over an 8-year period. Data were collected on the age, gender, and type of amblyopia, previous treatment received, and its duration. The compliance, tolerance, and adverse effects of OCL were recorded.
There were 12 patients of which 10 were male. The mean age at the time of OCL use was 47.3 months (range 26-86 months). Anisometropic amblyopia was present in 1, combined anisometropia and strabismus in 3, strabismic amblyopia in 5, and stimulus deprivation amblyopia in 3. All patients had conventional patching for a mean period of 14 months, followed by atropine penalization in nine patients for a mean period of 4 months. The mean duration of OCL use ranged from 2 weeks to 6 months. There were nine patients with visual improvement (75%). The mean improvement seen was 0.4 log of the minimum angle of resolution. There was no occlusion amblyopia. Four patients had conjunctivitis; one had a peripheral corneal abrasion.
The OCL is a useful adjunct in the treatment of amblyopia that is refractory to conventional treatment. The side effect profile is acceptable, but patients require close monitoring.
本研究旨在评估使用封闭式隐形眼镜（OCL）治疗传统遮盖疗法和阿托品压抑疗法失败的儿童难治性弱视的有效性，并评估其相关风险。
这是一项回顾性病例系列研究，纳入了8年间所有使用OCL治疗健眼的儿童。收集了患者的年龄、性别、弱视类型、既往接受的治疗及其持续时间等数据。记录了OCL的依从性、耐受性和不良反应。
共有12例患者，其中10例为男性。开始使用OCL时的平均年龄为47.3个月（范围26 - 86个月）。屈光参差性弱视1例，屈光参差合并斜视3例，斜视性弱视5例，形觉剥夺性弱视3例。所有患者均接受了平均14个月的传统遮盖治疗，9例患者随后接受了平均4个月的阿托品压抑治疗。OCL的平均使用时间为2周至6个月。9例患者视力改善（75%）。平均视力改善为0.4最小分辨角对数。未发生遮盖性弱视。4例患者发生结膜炎；1例发生周边角膜擦伤。
OCL是治疗传统疗法难治性弱视的一种有效辅助手段。其副作用可接受，但患者需要密切监测。
