Chung Young-Chul, Im Eun-Sung, Cho Gwang-Hyun, Ko Myung-Hwan
Department of Psychiatry, Chonbuk National University Medical School, Jeonju, South Korea.
World J Biol Psychiatry. 2007;8(1):48-50. doi: 10.1080/15622970600954044.
We report the case of a 30-year-old male schizophrenic patient with persistent auditory hallucinations (AHs) who had received two 1-Hz transcranial magnetic stimulations (TMS) to the left temporoparietal cortex. The patient had suffered from severe persistent AHs for more than 5 years with little improvement in response to various types of combination pharmacotherapy of antipsychotics. Upon commencement of TMS, however, the patient reported substantial improvement by the end of the third week of the treatment. The patient was discharged, but readmitted 6 months later because his AHs returned to their initial severity. A second run of TMS had no therapeutic effect. Further research is needed to establish the therapeutic duration of TMS treatment and to assess whether the second run of TMS after AH re-occurrence has therapeutic benefits.
我们报告了一例30岁男性精神分裂症患者的病例，该患者存在持续性幻听，曾接受两次对左侧颞顶叶皮质的1赫兹重复经颅磁刺激（TMS）。该患者患有严重持续性幻听超过5年，对抗精神病药物的各种联合药物治疗反应甚微，改善不明显。然而，在开始TMS治疗后，患者在治疗第三周结束时报告有显著改善。患者出院，但6个月后因幻听恢复到最初的严重程度而再次入院。第二轮TMS治疗没有治疗效果。需要进一步研究来确定TMS治疗的持续时间，并评估幻听复发后第二轮TMS治疗是否具有治疗益处。
