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用于治疗目的的麻风病分类方法。

Methods for the classification of leprosy for treatment purposes.

作者信息

Pardillo Fe Eleanor F, Fajardo Tranquilino T, Abalos Rodolfo M, Scollard David, Gelber Robert H

机构信息

Leonard Wood Memorial Center for Leprosy Research, Cebu City, Philippines.

出版信息

Clin Infect Dis. 2007 Apr 15;44(8):1096-9. doi: 10.1086/512809. Epub 2007 Mar 5.

DOI:10.1086/512809
PMID:17366457
Abstract

The World Health Organization advocates 2 leprosy treatment regimens on the basis of disease classification (as multibacillary or paucibacillary) by skin lesion count. This method, which, in the Philippines, results in a high prevalence (78%) of patients with multibacillary leprosy, was directly compared with classification using standard histopathological and microbiological criteria in 264 currently untreated patients with leprosy. Of those whose leprosy was classified as paucibacillary, 38%-51% of patients had multibacillary leprosy according to classic criteria and were thus at risk of undertreatment according to World Health Organization recommendations.

摘要

世界卫生组织根据皮肤损害计数对麻风病进行疾病分类(分为多菌型或少菌型),倡导两种麻风病治疗方案。在菲律宾,这种方法导致多菌型麻风病患者的患病率较高(78%)。在264名目前未接受治疗的麻风病患者中,将该方法与使用标准组织病理学和微生物学标准进行的分类直接进行了比较。在那些被分类为少菌型的麻风病患者中,根据经典标准,38%-51%的患者患有多菌型麻风病,因此按照世界卫生组织的建议,这些患者有治疗不足的风险。

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