Yaghoobi Reza, Omidian Mohammad, Sina Niloofar, Abtahian Seyyed-Arash, Panahi-Bazaz Mahmoud-Reza
Department of Dermatology, Jondi Shapour University of Medical Sciences, Ahwaz, Iran.
Arch Iran Med. 2007 Apr;10(2):246-9.
Olmsted syndrome is a rare congenital entity characterized by combination of symmetrical, sharply-defined palmoplantar keratoderma with flexion deformities of the digits, periorificial keratosis, perianal involvement, onychodystrophy, and variable leukokeratosis. Herein, we report two new related male patients--the third familial cases of Olmsted syndrome--one with the full-blown spectrum of the syndrome, and the other with early signs and symptoms of the disorder.
奥姆斯特德综合征是一种罕见的先天性疾病，其特征为对称性、边界清晰的掌跖角化病合并手指屈曲畸形、口周角化病、肛周受累、甲营养不良以及不同程度的白色角化病。在此，我们报告两例新的相关男性患者——奥姆斯特德综合征的第三例家族性病例——一例具有该综合征的全部典型症状，另一例有该疾病的早期体征和症状。
