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蜂蜜、橄榄油和蜂蜡混合物用于治疗痔疮和肛裂的安全性与有效性:一项初步研究。

The safety and efficacy of a mixture of honey, olive oil, and beeswax for the management of hemorrhoids and anal fissure: a pilot study.

作者信息

Al-Waili Noori S, Saloom Khelod S, Al-Waili Thia N, Al-Waili Ali N

机构信息

Al-Waili's Foundation for Science and Trading, New York, USA.

出版信息

ScientificWorldJournal. 2006 Feb 2;6:1998-2005. doi: 10.1100/tsw.2006.333.

DOI:10.1100/tsw.2006.333
PMID:17369999
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5944183/
Abstract

We have found that a mixture of honey, olive oil, and beeswax was effective for treatment of diaper dermatitis, psoriasis, eczema, and skin fungal infection. The mixture has antibacterial properties. A prospective pilot study was conducted to evaluate the therapeutic effect of topical application of the mixture on patients with anal fissure or hemorrhoids. Fifteen consecutive patients, 13 males and 2 females, median age 45 years (range: 28-70), who presented with anal fissure (5 patients) or first- to third-degree hemorrhoids (4 with first degree, 4 with second degree, and 2 with third degree), were treated with a 12-h application of a natural mixture containing honey, olive oil, and beeswax in ratio of 1:1:1(v/v/v). Bleeding, itching, edema, and erythema were measured using a scoring method: 0 = none, 1 = mild, 2 = moderate, 3 = severe, and 4 = very severe. The pain score was checked using a visual analog scale (minimum = 0, maximum = 10). Efficacy of treatment was assessed by comparing the symptoms' score before and after treatment; at weekly intervals for a maximum of 4 weeks. The patients were observed for evidence of any adverse effect such as appearance of new signs and symptoms, or worsening of the existing symptoms. The honey mixture significantly reduced bleeding and relieved itching in patients with hemorrhoids. Patients with anal fissure showed significant reduction in pain, bleeding, and itching after the treatment. No side effect was reported with use of the mixture. We conclude that a mixture of honey, olive oil, and beeswax is safe and clinically effective in the treatment of hemorrhoids and anal fissure, which paves the way for further randomized double blind studies.

摘要

我们发现蜂蜜、橄榄油和蜂蜡的混合物对治疗尿布皮炎、牛皮癣、湿疹和皮肤真菌感染有效。该混合物具有抗菌特性。进行了一项前瞻性试点研究,以评估局部应用该混合物对肛裂或痔疮患者的治疗效果。连续15例患者,13例男性和2例女性,中位年龄45岁(范围:28 - 70岁),患有肛裂(5例)或一至三度痔疮(4例一度、4例二度和2例三度),接受了含蜂蜜、橄榄油和蜂蜡比例为1:1:1(v/v/v)的天然混合物12小时的治疗。采用评分方法测量出血、瘙痒、水肿和红斑:0 = 无,1 = 轻度,2 = 中度,3 = 重度,4 = 非常重度。使用视觉模拟量表检查疼痛评分(最小值 = 0,最大值 = 10)。通过比较治疗前后症状评分评估治疗效果;每周进行一次,最长4周。观察患者是否有任何不良反应的迹象,如出现新的体征和症状或现有症状恶化。蜂蜜混合物显著减少了痔疮患者的出血并缓解了瘙痒。肛裂患者治疗后疼痛、出血和瘙痒明显减轻。使用该混合物未报告有副作用。我们得出结论,蜂蜜、橄榄油和蜂蜡的混合物在治疗痔疮和肛裂方面是安全且临床有效的,这为进一步的随机双盲研究铺平了道路。

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