Sivanesan D, Begum V Hazeena
Unit of Biochemistry, Department of Siddha Medicine, Faculty of Science, Tamil University, Thanjavur 613005, India.
Indian J Exp Biol. 2007 Mar;45(3):299-303.
G. gynandra extract was found to potentially diminish the rate of lipid peroxidation, with a significant increase in the levels of enzymatic (superoxide dismutase, catalase and glutathione peroxidase) and non-enzymatic (reduced glutathione vitamins E and C, and uric acid) antioxidants, which were found, altered during aflatoxin B1 (AFB1) injection. The result confirmed that G. gynandra extract exerts its chemopreventive efficacy by preventing the rate of lipid peroxidation and influenced the enzymatic and non-enzymatic antioxidants in AFB1 induced male albino rats.
发现假败酱提取物有可能降低脂质过氧化速率，同时酶促抗氧化剂（超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶）和非酶促抗氧化剂（还原型谷胱甘肽、维生素E和C以及尿酸）水平显著增加，这些抗氧化剂在注射黄曲霉毒素B1（AFB1）后发生了改变。结果证实，假败酱提取物通过防止脂质过氧化速率发挥其化学预防功效，并影响AFB1诱导的雄性白化大鼠体内的酶促和非酶促抗氧化剂。
