老年人黄斑色素光密度的估计：假晶状体眼受试者的重测变异性及光学模糊的影响
Estimation of macular pigment optical density in the elderly: test-retest variability and effect of optical blur in pseudophakic subjects.
作者信息
Gallaher Kevin T, Mura Marco, Todd Wm Andrew, Harris Tarsha L, Kenyon Emily, Harris Tamara, Johnson Karen C, Satterfield Suzanne, Kritchevsky Stephen B, Iannaccone Alessandro
机构信息
Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, 930 Madison Avenue, Suite 731, Memphis, TN 38163, USA.
出版信息
Vision Res. 2007 Apr;47(9):1253-9. doi: 10.1016/j.visres.2007.01.013. Epub 2007 Mar 21.
Abstract
The reproducibility of macular pigment optical density (MPOD) estimates in the elderly was assessed in 40 subjects (age: 79.1+/-3.5). Test-retest variability was good (Pearson's r coefficient: 0.734), with an average coefficient of variation (CV) of 18.4% and an intraclass correlation coefficient (ICC) of 0.96. The effect of optical blur on MPOD estimates was investigated in 22 elderly pseudophakic subjects (age: 79.9+/-3.6) by comparing the baseline MPOD, obtained with an optimal correction, with MPODs obtained with a +/-1.00-diopter optical blur. This optical blur did not cause differences in the MPOD estimates, its accuracy, or test duration.
摘要
对40名受试者（年龄：79.1±3.5岁）的老年人黄斑色素光密度（MPOD）估计值的可重复性进行了评估。重测变异性良好（皮尔逊r系数：0.734），平均变异系数（CV）为18.4%，组内相关系数（ICC）为0.96。通过比较最佳矫正下获得的基线MPOD与±1.00屈光度光学模糊下获得的MPOD，在22名老年人工晶状体植入受试者（年龄：79.9±3.6岁）中研究了光学模糊对MPOD估计值的影响。这种光学模糊在MPOD估计值、其准确性或测试持续时间方面未造成差异。
相似文献
1
Estimation of macular pigment optical density in the elderly: test-retest variability and effect of optical blur in pseudophakic subjects.老年人黄斑色素光密度的估计：假晶状体眼受试者的重测变异性及光学模糊的影响
Vision Res. 2007 Apr;47(9):1253-9. doi: 10.1016/j.visres.2007.01.013. Epub 2007 Mar 21.
2
Macular pigment optical density in the elderly: findings in a large biracial Midsouth population sample.老年人黄斑色素光密度：来自中南地区一个大型双种族人群样本的研究结果
Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1458-65. doi: 10.1167/iovs.06-0438.
3
Interocular agreement in melanin and macular pigment optical density.黑色素和黄斑色素光密度的眼间一致性。
Exp Eye Res. 2007 May;84(5):934-8. doi: 10.1016/j.exer.2007.01.020. Epub 2007 Feb 7.
4
Clinical evaluation of the MPS 9000 Macular Pigment Screener.MPS 9000 黄斑色素筛检仪的临床评估。
Br J Ophthalmol. 2010 Jun;94(6):753-6. doi: 10.1136/bjo.2009.175901.
5
Clinical evaluation of the MacuScope macular pigment densitometer.MacuScope 黄斑色素密度计的临床评估。
Br J Ophthalmol. 2010 Mar;94(3):328-31. doi: 10.1136/bjo.2009.167213. Epub 2009 Oct 22.
6
Macular pigment measurement by heterochromatic flicker photometry in older subjects: the carotenoids and age-related eye disease study.老年受试者中通过异色闪烁光度法测量黄斑色素：类胡萝卜素与年龄相关性眼病研究
Invest Ophthalmol Vis Sci. 2004 Feb;45(2):531-8. doi: 10.1167/iovs.03-0762.
7
Macular pigment optical density in a Chinese sample.
Curr Eye Res. 2005 Sep;30(9):799-805. doi: 10.1080/02713680590968439.
8
In vivo macular pigment measurements: a comparison of resonance Raman spectroscopy and heterochromatic flicker photometry.体内黄斑色素测量：共振拉曼光谱法与异色闪烁光度法的比较
Br J Ophthalmol. 2007 Apr;91(4):485-90. doi: 10.1136/bjo.2006.090936. Epub 2006 Jul 6.
9
The Macular Assessment Profile test - a new VDU-based technique for measuring the spatial distribution of the macular pigment, lens density and rapid flicker sensitivity.黄斑评估图测试 - 一种新的基于 VDU 的技术，用于测量黄斑色素、晶状体密度和快速闪烁敏感性的空间分布。
Ophthalmic Physiol Opt. 2010 Sep;30(5):470-83. doi: 10.1111/j.1475-1313.2010.00748.x.
10
Macular pigment optical density measurements: evaluation of a device using heterochromatic flicker photometry.黄斑色素光学密度测量：使用对比闪光视亮度计评估一种设备。
Eye (Lond). 2011 Jan;25(1):105-12. doi: 10.1038/eye.2010.164. Epub 2010 Nov 5.
引用本文的文献
1
Macular Pigment Optical Density and Measures of Macular Function: Test-Retest Variability, Cross-Sectional Correlations, and Findings from the Zeaxanthin Pilot Study of Response to Supplementation (ZEASTRESS-Pilot).黄斑色素光密度与黄斑功能测量：重测变异性、横断面相关性以及叶黄素补充反应试点研究（ZEASTRESS-试点）的结果
Foods. 2016 Apr 29;5(2):32. doi: 10.3390/foods5020032.
2
Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration.视网膜色素上皮细胞和小胶质细胞表达CD5抗原样蛋白，这是年龄相关性黄斑变性中的一种新型自身抗原。
Exp Eye Res. 2017 Feb;155:64-74. doi: 10.1016/j.exer.2016.12.006. Epub 2016 Dec 15.
3
An exploratory study evaluating the effects of macular carotenoid supplementation in various retinal diseases.一项评估黄斑类胡萝卜素补充剂对各种视网膜疾病影响的探索性研究。
Clin Ophthalmol. 2016 May 11;10:835-44. doi: 10.2147/OPTH.S102798. eCollection 2016.
4
Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis.年龄相关性黄斑变性中的循环自身抗体识别与自噬、免疫调节以及抗氧化应激和细胞凋亡保护相关的人黄斑组织抗原。
PLoS One. 2015 Dec 30;10(12):e0145323. doi: 10.1371/journal.pone.0145323. eCollection 2015.
5
The use of heterochromatic flicker photometry to determine macular pigment optical density in a healthy Australian population.应用异染色闪烁光度法测定澳大利亚健康人群黄斑色素的光学密度。
Graefes Arch Clin Exp Ophthalmol. 2014 Mar;252(3):417-21. doi: 10.1007/s00417-013-2554-6. Epub 2014 Jan 5.
6
The macular pigment optical density spatial profile and increasing age.黄斑色素光密度空间分布与年龄增长。
Graefes Arch Clin Exp Ophthalmol. 2014 Mar;252(3):383-8. doi: 10.1007/s00417-013-2471-8. Epub 2013 Oct 1.
7
Using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration.利用遗传变异和环境风险因素数据来识别与年龄相关的黄斑变性高危个体。
PLoS One. 2011 Mar 24;6(3):e17784. doi: 10.1371/journal.pone.0017784.
8
Measuring macular pigment optical density in vivo: a review of techniques.活体黄斑色素光密度测量：技术综述。
Graefes Arch Clin Exp Ophthalmol. 2011 Mar;249(3):315-47. doi: 10.1007/s00417-010-1577-5. Epub 2011 Jan 8.
本文引用的文献
1
Macular pigment optical density in the elderly: findings in a large biracial Midsouth population sample.老年人黄斑色素光密度：来自中南地区一个大型双种族人群样本的研究结果
Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1458-65. doi: 10.1167/iovs.06-0438.
2
On the age dependency of the macular pigment optical density.关于黄斑色素光密度的年龄依赖性。
Exp Eye Res. 2005 Nov;81(5):602-9. doi: 10.1016/j.exer.2005.03.019. Epub 2005 Jul 15.
3
The mechanism of presbyopia.老花眼的机制。
Prog Retin Eye Res. 2005 May;24(3):379-93. doi: 10.1016/j.preteyeres.2004.11.001. Epub 2004 Dec 19.
4
Resonance Raman measurement of macular carotenoids in the living human eye.活体人眼中黄斑类胡萝卜素的共振拉曼测量。
Arch Biochem Biophys. 2004 Oct 15;430(2):163-9. doi: 10.1016/j.abb.2004.07.004.
5
Autofluorescence method to measure macular pigment optical densities fluorometry and autofluorescence imaging.测量黄斑色素光密度的自体荧光方法：荧光测定法和自体荧光成像。
Arch Biochem Biophys. 2004 Oct 15;430(2):156-62. doi: 10.1016/j.abb.2004.05.016.
6
Objective determination of the macular pigment optical density using fundus reflectance spectroscopy.使用眼底反射光谱法客观测定黄斑色素光密度。
Arch Biochem Biophys. 2004 Oct 15;430(2):149-55. doi: 10.1016/j.abb.2004.04.029.
7
Macular pigment assessment by motion photometry.
Arch Biochem Biophys. 2004 Oct 15;430(2):143-8. doi: 10.1016/j.abb.2004.06.024.
8
Heterochromatic flicker photometry.异色闪烁光度测定法
Arch Biochem Biophys. 2004 Oct 15;430(2):137-42. doi: 10.1016/j.abb.2004.04.003.
9
Macular pigments: their characteristics and putative role.黄斑色素：其特性及假定作用。
Prog Retin Eye Res. 2004 Sep;23(5):533-59. doi: 10.1016/j.preteyeres.2004.05.004.
10
Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy: a pilot study.患有和未患有年龄相关性黄斑病变的受试者对叶黄素补充剂的血浆和黄斑反应：一项初步研究。
Exp Eye Res. 2004 Jul;79(1):21-7. doi: 10.1016/j.exer.2004.03.001.
Zotero 插件