Hernández-Garduño Eduardo, Pérez-Guzmán Carlos
TB Control, British Columbia Centre for Disease Control, 1066-655 W 12th Avenue, Vancouver, BC, Canada V5Z 4R4.
Med Hypotheses. 2007;69(4):869-72. doi: 10.1016/j.mehy.2007.02.006. Epub 2007 Mar 21.
Different risk factors have been identified as associated with tuberculosis (TB), an important and common one is malnutrition, however, the causes of malnutrition have not been studied in detail, the lack of food and poverty are among the most frequent in developing countries but others are yet to be identified. We hypothesized that chronic lack of appetite can be one of the causes of malnutrition associated to TB and therefore be a potential independent risk factor for latent tuberculosis infection (LTBI) or TB disease. If this is true, contact subjects with LTBI who have poor appetite will be at higher risk for getting the disease and people with the disease will be at risk for poor treatment outcomes.
不同的风险因素已被确定与结核病（TB）相关，一个重要且常见的因素是营养不良。然而，营养不良的原因尚未得到详细研究。在发展中国家，食物短缺和贫困是最常见的原因，但其他原因尚未明确。我们假设长期食欲不振可能是与结核病相关的营养不良的原因之一，因此可能是潜伏性结核感染（LTBI）或结核病的一个潜在独立风险因素。如果这是真的，那么食欲不佳的LTBI接触者患该病的风险会更高，而患该病的人则有治疗效果不佳的风险。
