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1993年至2006年希腊的C群脑膜炎球菌病:多数儿科医生采用的非官方单剂量疫苗接种方案的影响

Meningococcal group C disease in Greece during 1993-2006: the impact of an unofficial single-dose vaccination scheme adopted by most paediatricians.

作者信息

Kafetzis D A, Stamboulidis K N, Tzanakaki G, Kourea Kremastinou J, Skevaki C L, Konstantopoulos A, Tsolia M

机构信息

Second Department of Pediatrics, University of Athens, P. & A. Kyriakou Children's Hospital, Athens, Greece.

出版信息

Clin Microbiol Infect. 2007 May;13(5):550-2. doi: 10.1111/j.1469-0691.2007.01704.x. Epub 2007 Mar 22.

DOI:10.1111/j.1469-0691.2007.01704.x
PMID:17378929
Abstract

The aim of this study was to evaluate the impact of the meningococcal C conjugate vaccine on the epidemiology of meningococcal C disease in Greece. Data from the National Reference Laboratory for Meningococcal Disease and a questionnaire distributed to Greek paediatricians were assessed. Since the introduction of the vaccine in 2001, 72% of Greek paediatricians have administered it as one single dose to patients aged > or =12 months. This vaccination scheme has probably contributed to a dramatic decrease in the number of meningococcal C infections, which reached zero in 2004.

摘要

本研究的目的是评估脑膜炎球菌C结合疫苗对希腊脑膜炎球菌C病流行病学的影响。对来自国家脑膜炎球菌病参考实验室的数据以及分发给希腊儿科医生的一份调查问卷进行了评估。自2001年引入该疫苗以来,72%的希腊儿科医生已将其作为单剂量疫苗接种给年龄大于或等于12个月的患者。这种疫苗接种方案可能促成了脑膜炎球菌C感染病例数的大幅下降,2004年该感染病例数降为零。

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