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尿流改道:选择、患者选择及结果

Urinary diversion: options, patient selection, and outcomes.

作者信息

Parekh Dipen J, Donat S Machele

机构信息

Department of Urology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

出版信息

Semin Oncol. 2007 Apr;34(2):98-109. doi: 10.1053/j.seminoncol.2006.12.010.

Abstract

Improved survival following radical cystectomy for bladder cancer as a result of advancements in combination chemotherapy and surgical technique has resulted in a philosophical change in the surgeon's approach to urinary diversion selection. Aims have evolved from the mere diversion of urine to a functional bowel conduit such as an ileal conduit or ureterosigmoidostomy, to providing the optimal diversion for the patient's quality of life. While quality of life is important, one must also consider the stage of cancer and individual patient comorbidities. Which diversion provides the best local cancer control, the lowest potential for complications (short and long term), and the easiest emotional adjustment in lifestyle while still allowing the timely completion of chemotherapy and therapeutic goals? A multidisciplinary approach to diversion selection that includes the patient, the medical oncologist, radiation oncologist, internist, and surgeon is ideal. We describe the three most commonly used types of diversions today, including conduits, continent cutaneous reservoirs, and orthotopic urethral diversions, as well as issues relative to patient selection and functional outcomes in patients undergoing radical cystectomy for the treatment of bladder cancer.

摘要

联合化疗和手术技术的进步使膀胱癌根治性膀胱切除术后的生存率提高,这导致了外科医生在选择尿流改道方式时观念的转变。目标已从单纯的尿液转流至功能性肠管通道(如回肠通道或输尿管乙状结肠吻合术),转变为为患者的生活质量提供最佳的尿流改道方式。虽然生活质量很重要,但还必须考虑癌症分期和患者个体的合并症。哪种尿流改道方式能提供最佳的局部癌症控制、最低的并发症(短期和长期)发生风险,以及在仍能及时完成化疗和治疗目标的同时,最易于患者进行生活方式的情绪调整?采用包括患者、医学肿瘤学家、放射肿瘤学家、内科医生和外科医生在内的多学科方法来选择尿流改道方式是理想的。我们描述了当今最常用的三种尿流改道类型,包括通道、可控性皮肤贮尿囊和原位尿道改道,以及与接受膀胱癌根治性膀胱切除术患者的选择和功能结果相关的问题。

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