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妊娠相关乳腺癌的管理

Management of pregnancy-associated breast cancer.

作者信息

Jones Alison Louise

机构信息

Department of Oncology, Royal Free and University College Hospitals, London, UK.

出版信息

Breast. 2006 Dec;15 Suppl 2:S47-52. doi: 10.1016/S0960-9776(07)70018-8.

Abstract

Breast cancer during pregnancy remains a challenge for clinicians and a difficult experience for women and the families. Any breast symptom during pregnancy warrants triple assessment and any lump should have a definite diagnosis. If cancer is diagnosed it is usually possible to continue with the pregnancy without compromising any of the treatment modalities (except radiotherapy). The outcome for women diagnosed with breast cancer during pregnancy is the same as for age and stage-matched non-pregnant counterparts. There is no evidence of adverse foetal outcome if chemotherapy is given during the second or third trimester. However, the reported series are relatively small and more systematic long-term follow-up is needed.

摘要

孕期乳腺癌对临床医生而言仍是一项挑战,对女性及其家庭来说也是一段艰难经历。孕期出现的任何乳房症状都需要进行三联评估,任何肿块都应明确诊断。如果确诊为癌症,通常可以在不影响任何治疗方式(放射治疗除外)的情况下继续妊娠。孕期被诊断为乳腺癌的女性,其预后与年龄和分期匹配的非孕期女性相同。没有证据表明在孕中期或孕晚期进行化疗会对胎儿产生不良影响。然而,所报道的病例系列相对较小,需要更系统的长期随访。

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