Ring Alistair
Sussex Cancer Centre, Royal Sussex County Hospital, Eastern Road, Brighton BN2 5BE, UK.
Breast. 2007 Dec;16 Suppl 2:S155-8. doi: 10.1016/j.breast.2007.07.025. Epub 2007 Aug 21.
The frequency with which breast cancer is diagnosed in pregnant women is low (in the region of 1 in 1000 pregnancies), but the management of these women presents a considerable challenge to those involved in their care. Women frequently present with tumours displaying adverse pathological prognostic features. Initial investigation may be carried out as for non-pregnant women, but with particular attention paid to the risks of exposure to the foetus of ionizing radiation. Surgery can be carried out with seemingly little increased risk to the mother or foetus, but radiotherapy is usually avoided. In terms of short-term complications chemotherapy may be given relatively safely when administered outside of the first trimester and not around the time of delivery. However, the principle concern with all of these interventions is what the long-term implications for the newborn might be.
孕妇被诊断出患有乳腺癌的频率较低（约为每1000次怀孕中有1例），但对这些孕妇的管理给参与其护理的人员带来了相当大的挑战。这些女性经常出现具有不良病理预后特征的肿瘤。初始检查可以像对非孕妇一样进行，但要特别注意电离辐射对胎儿的暴露风险。手术对母亲或胎儿的风险似乎增加不多，但通常避免放疗。就短期并发症而言，在孕早期以外且不在分娩前后进行化疗可能相对安全。然而，所有这些干预措施主要关注的是对新生儿可能产生的长期影响。
