Cammarota Giovanni, Masala Giovanna, Cianci Rossella, Palli Domenico, Capaccio Pasquale, Schindler Antonio, Cuoco Lucio, Galli Jacopo, Ierardi Enzo, Cannizzaro Oreste, Caselli Michele, Dore Maria P, Bendinelli Benedetta, Gasbarrini Giovanni
Institute of Internal Medicine, Catholic University of Medicine and Surgery, Rome, Italy.
Gastroenterology. 2007 Mar;132(3):890-8. doi: 10.1053/j.gastro.2007.01.047.
A specific, occupation-related susceptibility of professional singers to experience gastroesophageal reflux was hypothesized. We investigated the prevalence of gastroesophageal reflux symptoms in a series of professional opera choristers in comparison with a general population sample.
A total of 351 professional opera choristers from well-known chorus in different Italian regions were identified and a sample of 578 subjects residing in the same areas with a similar distribution in age and sex was selected. Reflux symptoms in the year preceding the survey together with selected individual characteristics and lifestyle habits were investigated in both study groups through a structured questionnaire. Prevalence rate ratios, adjusted for sex, age, body mass index, smoking status, alcohol consumption, and other confounding factors, were computed.
Opera choristers reported a statistically significant higher prevalence of heartburn, regurgitation, cough, and hoarse voice than the population sample, with adjusted prevalent rate ratios of 1.60 (95% confidence interval [CI], 1.32-1.94), 1.81 (95% CI, 1.42-2.30), 1.40 (95% CI, 1.18-1.67), and 2.45 (95% CI, 1.97-3.04), respectively. Regurgitation appeared to be associated consistently with the cumulative lifetime duration of singing activity (P = .04) and with the weekly duration of singing activity (P = .005) when different multivariate models were applied.
Opera choristers reported a higher prevalence of reflux symptoms than the population sample. Future studies will be needed to clarify whether gastroesophageal reflux in professional opera choristers is stress-induced and therefore may be considered as a work-related disease.
有假设认为职业歌手存在与职业相关的特定胃食管反流易感性。我们调查了一系列职业歌剧合唱队员中胃食管反流症状的患病率,并与普通人群样本进行比较。
确定了来自意大利不同地区知名合唱团的351名职业歌剧合唱队员,并选取了578名居住在同一地区、年龄和性别分布相似的受试者作为样本。通过结构化问卷对两个研究组在调查前一年的反流症状以及选定的个人特征和生活习惯进行了调查。计算了经性别、年龄、体重指数、吸烟状况、饮酒量和其他混杂因素调整后的患病率比值。
歌剧合唱队员报告的烧心、反流、咳嗽和声音嘶哑的患病率在统计学上显著高于人群样本,调整后的患病率比值分别为1.60(95%置信区间[CI],1.32 - 1.94)、1.81(95%CI,1.42 - 2.30)、1.40(95%CI,1.18 - 1.67)和2.45(95%CI,1.97 - 3.04)。当应用不同的多变量模型时,反流似乎始终与歌唱活动的累积终生时长(P = .04)和每周歌唱活动时长(P = .005)相关。
歌剧合唱队员报告的反流症状患病率高于人群样本。未来需要进一步研究以阐明职业歌剧合唱队员的胃食管反流是否由压力引起,因此是否可被视为一种与工作相关的疾病。