Loor Alexandra Corojan, Nedelcuţ Sebastian, Dumitraşcu Dan Lucian
2 Medical Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Med Pharm Rep. 2020 Apr;93(2):145-149. doi: 10.15386/mpr-1370. Epub 2020 Apr 22.
Opera singers are at risk to develop gastroesophageal reflux, because of the vocational challenges during singing. The singers are reluctant to be submitted to pH-metry fearing throat injuries. We evaluated the gastroesophageal reflux in vocal opera students using a non-invasive salivary test.
A prospective, case-control study was carried out in 30 vocal opera students from the Music Academy of the city Cluj-Napoca, Romania, enrolled in the "canto" section.
For control, 20 medical students and residents were enrolled. Each subject filled in a questionnaire and gave saliva samples for the salivary test Peptest™ (RD Biomed). The statistical analysis was made using program R version 3.2.1 (2015-06-18).
According to salivary Peptest, vocal opera students had a higher prevalence of gastro-esophageal reflux than the control group (96.67% versus 30%; 29 from 30 vs 14 from 20), P<0.001. Only 50% (15 of 30) of the vocal opera students reported reflux symptoms.
Salivary Peptest confirmed a higher prevalence of gastroesophageal reflux in vocal opera students, although not all of them reported reflux symptoms.
由于唱歌过程中的职业挑战，歌剧演唱家有患胃食管反流病的风险。歌手们因担心喉咙受伤而不愿接受pH值测定。我们使用一种非侵入性唾液检测方法评估了声乐歌剧专业学生的胃食管反流情况。
在罗马尼亚克卢日-纳波卡市音乐学院30名就读于“歌唱”专业的声乐歌剧专业学生中开展了一项前瞻性病例对照研究。
选取20名医学生和住院医师作为对照。每位受试者填写一份问卷，并提供唾液样本用于唾液检测Peptest™（RD Biomed公司）。使用R版本3.2.1（2015年6月18日）软件进行统计分析。
根据唾液Peptest检测结果，声乐歌剧专业学生的胃食管反流患病率高于对照组（96.67%对30%；30人中有29人，20人中有14人），P<0.001。只有50%（30人中的15人）的声乐歌剧专业学生报告有反流症状。
唾液Peptest证实声乐歌剧专业学生的胃食管反流患病率较高，尽管并非所有学生都报告有反流症状。
