Ballon Jacob S, Kaur Tejal, Marks Iliana I, Cadenhead Kristin S
University of California, San Diego, Department of Psychiatry, San Diego, CA 92093-0810, USA.
Psychiatry Res. 2007 May 30;151(1-2):29-35. doi: 10.1016/j.psychres.2006.10.012. Epub 2007 Mar 26.
Deficits in social functioning are potential risk factors for schizophrenia. Social functioning was assessed in 55 individuals "at risk" for schizophrenia, 16 first episode patients with schizophrenia and 45 normal comparison subjects. The Social Adjustment Inventory for Children and Adolescents (SAICA) was administered to adolescents <18 and the Social Adjustment Scale (SAS-SR) to young adults >17. The at risk and first episode groups significantly differed from the normal subjects on measures of social functioning in the domains of peer, family, work and school relationships. Individuals at risk for schizophrenia have significant functional deficits which may be potential indicators of increased vulnerability for psychosis.
社交功能缺陷是精神分裂症的潜在风险因素。对55名有精神分裂症“风险”的个体、16名首次发作的精神分裂症患者和45名正常对照受试者进行了社交功能评估。对18岁以下的青少年使用儿童和青少年社会适应量表(SAICA),对17岁以上的年轻人使用社会适应量表(SAS-SR)。在同伴、家庭、工作和学校关系等领域的社交功能测量方面,有风险组和首次发作组与正常受试者有显著差异。有精神分裂症风险的个体存在明显的功能缺陷,这可能是精神病易感性增加的潜在指标。