Cho J Y, Min J Y, Lee Y-H, McCrindle B, Hornberger L K, Yoo S-J
Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ultrasound Obstet Gynecol. 2007 Jun;29(6):634-8. doi: 10.1002/uog.3979.
To present the normative data of the transverse diameter of the developing fetal thymus.
In this prospective study, the maximum transverse diameter of the thymus was measured by one sonologist in 376 normal fetuses between 19 and 38 weeks of gestation. We assessed the relationship of the transverse thymic diameter with gestational age (GA), biparietal diameter, femur length and abdominal circumference using general linear regression modeling. The predicted mean and 95% reference range of thymic diameter at each GA were calculated from the regression equation.
Measurements of the transverse diameter were possible in 352 of the 376 (94%) fetuses. The transverse diameter of the fetal thymus increased with increasing GA and fetal size parameters in a linear manner. The regression equation for transverse diameter of the thymus as a function of GA was: thymic diameter (cm) = 0.15 x GA (weeks) - 1.59 (r(2) = 0.86, P < 0.001).
The transverse diameter of the fetal thymus is easy to measure; this study presents normative data.
呈现发育中胎儿胸腺横径的规范数据。
在这项前瞻性研究中，由一名超声科医生对376例孕19至38周的正常胎儿测量胸腺的最大横径。我们使用一般线性回归模型评估胸腺横径与孕周（GA）、双顶径、股骨长度和腹围之间的关系。根据回归方程计算每个孕周时胸腺直径的预测均值和95%参考范围。
376例胎儿中有352例（94%）成功测量了横径。胎儿胸腺横径随孕周和胎儿大小参数的增加呈线性增加。胸腺横径作为孕周函数的回归方程为：胸腺直径（cm）= 0.15×孕周（周） - 1.59（r² = 0.86，P < 0.001）。
胎儿胸腺横径易于测量；本研究给出了规范数据。
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