Wigfield R E, Fleming P J, Berry P J, Rudd P T, Golding J
Institute of Child Health, Bristol.
BMJ. 1992 Feb 1;304(6822):282-3. doi: 10.1136/bmj.304.6822.282.
To examine the impact of changing practice with regard to infant sleeping position on mortality from the sudden infant death syndrome.
A population based study of all infants dying suddenly and unexpectedly during February 1990 to July 1991, and two groups of controls; one comprising every 125th baby born to Avon residents and the other comprising pairs of infants matched to each index case for age, neighbourhood, and date of study. Information about sleeping position was collected at home visits soon after the index baby's death or, for the population based controls, on several occasions in the first six months of life. The design was comparable to that of an earlier study of the same population.
County of Avon.
35 infants who died suddenly and unexpectedly (32 of the sudden infant death syndrome), 70 matched controls, and 152 population based controls.
The prevalence of prone sleeping in the matched controls was much lower than that found in an earlier study in Avon (28% (18/64) 1990-1 v 58% (76/131) 1987-9; p less than 0.001) and was comparable with the prevalence in population based controls (29%). This would be expected to lead to a reduction in the incidence of the sudden infant death syndrome to 2.0/1000 live births (95% confidence interval 1.8/1000 to 2.5/1000). The actual mortality fell from 3.5/1000 in 1987-9 to 1.7/1000.
The fall in mortality can be almost entirely accounted for by the reduction in prone sleeping, suggesting a causal relation exists between them. Side and supine positions confer protection but the side position is unstable and the infant may roll prone. We therefore recommend supine as the safest sleeping position for babies.
研究婴儿睡眠姿势的改变对婴儿猝死综合征死亡率的影响。
对1990年2月至1991年7月期间所有突然意外死亡的婴儿以及两组对照进行基于人群的研究;一组为埃文地区每125个出生婴儿中的一个,另一组为按年龄、社区和研究日期与每个索引病例匹配的成对婴儿。在索引婴儿死亡后不久进行家访时收集睡眠姿势信息,对于基于人群的对照,则在生命的前六个月内多次收集。该设计与对同一人群的早期研究相似。
埃文郡。
35例突然意外死亡的婴儿(32例为婴儿猝死综合征)、70例匹配对照和152例基于人群的对照。
匹配对照中俯卧睡眠的发生率远低于埃文地区早期研究中的发生率(1990 - 1年为28%(18/64),而1987 - 9年为58%(76/131);p<0.001),与基于人群的对照中的发生率相当(29%)。这预计会使婴儿猝死综合征的发病率降至2.0/1000活产(95%可信区间为1.8/1000至2.5/1000)。实际死亡率从1987 - 9年的3.5/1000降至1.7/1000。
死亡率的下降几乎完全可归因于俯卧睡眠的减少,表明两者之间存在因果关系。侧卧和仰卧姿势可提供保护,但侧卧姿势不稳定,婴儿可能会翻滚至俯卧。因此,我们建议仰卧是婴儿最安全的睡眠姿势。