Fu Wenqun, Wu Keqiang, Duan Jun
South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
Biochem Biophys Res Commun. 2007 May 18;356(4):843-50. doi: 10.1016/j.bbrc.2007.03.010. Epub 2007 Mar 12.
Histone acetylation levels are determined by the action of histone acetyltransferases and histone deacetylases (HDACs). Sequence similarity and profile searching tools were used to analyze the genome sequence of rice (Oryzae sativa) for genes encoding HDAC proteins. The rice RPD3/HDA1-family HDAC proteins can be divided into four classes based on sequence similarity and phylogenetic analysis of sequences obtained from the rice genome. The spatial expression pattern of rice HDACs genes indicated that some HDAC genes have different expression profiles. Furthermore, our analysis indicated that expression of HDA705, HDT701, and HDT702 could be affected by salicylic acid, jasmonic acid or abscisic acid. Expression of HDA714, SRT702, and SRT701 could be modulated by abiotic stresses, such as cold, mannitol and salt. These results indicate that different HDAC genes have distinct expression patterns and members of rice HDAC families may be involved in plant response to environmental stresses.
组蛋白乙酰化水平由组蛋白乙酰转移酶和组蛋白去乙酰化酶（HDACs）的作用决定。利用序列相似性和图谱搜索工具分析水稻（Oryzae sativa）基因组序列中编码HDAC蛋白的基因。基于从水稻基因组获得的序列的相似性和系统发育分析，水稻RPD3/HDA1家族的HDAC蛋白可分为四类。水稻HDACs基因的空间表达模式表明，一些HDAC基因具有不同的表达谱。此外，我们的分析表明，HDA705、HDT701和HDT702的表达可能受水杨酸、茉莉酸或脱落酸的影响。HDA714、SRT702和SRT701的表达可受非生物胁迫（如寒冷、甘露醇和盐）的调节。这些结果表明，不同的HDAC基因具有不同的表达模式，水稻HDAC家族成员可能参与植物对环境胁迫的响应。
