Chandramohan Anuradha, Eapen Anu, Govil Shalini, Govil Sanjay, Jeyaseelan Visalakshi
Department of Radio-diagnosis, Christian Medical College and Hospital, Vellore 632 002, India.
Indian J Gastroenterol. 2007 Jan-Feb;26(1):22-5.
With the increasing numbers of living-related donor liver transplantation, accurate means of calculating standard liver volume (SLV) based on patient body indices becomes important. Three formulae reported in literature for this purpose have been derived from studies on Western and Japanese populations.
To assess the existing formulae for calculation of SLV in Indian population.
Total liver volume (TLV) of 238 patients was measured using axial helical CT images obtained for conditions unrelated to the hepatobiliary system. Body surface area (BSA) was calculated from height and weight. Measurements obtained using CT were compared with the SLV calculated based on the previously reported formulae.
Though there was significant difference (p< 0.001) between the TLV obtained by CT and the SLV calculated using the three formulae, they also showed good agreement. On an average the formula derived from the Japanese population underestimated the SLV by 63 (202) cc (p< 0.001). Regression models for SLV (SLV = 243 + [186 x BSA] + [11.4 x Weight], SLV = 375.23 + [14.24 x body weight], SLV = -204.092 + [874.461 x BSA]) were derived from the data obtained from our population. Age and gender had no effect on the SLV.
Formulae derived from Japanese population for calculation of SLV is not suitable for the Indian population. The newly described formulae may prove useful in the Indian population.
随着活体亲属供肝移植数量的增加，基于患者身体指标准确计算标准肝体积（SLV）的方法变得至关重要。文献中报道的用于此目的的三个公式是从对西方和日本人群的研究中推导出来的。
评估印度人群中计算SLV的现有公式。
使用为与肝胆系统无关的情况获取的轴向螺旋CT图像测量238例患者的全肝体积（TLV）。根据身高和体重计算体表面积（BSA）。将CT测量结果与根据先前报道的公式计算的SLV进行比较。
尽管CT获得的TLV与使用这三个公式计算的SLV之间存在显著差异（p<0.001），但它们也显示出良好的一致性。平均而言，源自日本人群的公式使SLV低估了63（202）cc（p<0.001）。根据我们人群获得的数据推导出了SLV的回归模型（SLV = 243 + [186×BSA] + [11.4×体重]，SLV = 375.23 + [14.24×体重]，SLV = -204.092 + [874.461×BSA]）。年龄和性别对SLV没有影响。
源自日本人群用于计算SLV的公式不适用于印度人群。新描述的公式可能对印度人群有用。
