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胸膜肺炎放线杆菌5b型荚膜多糖的结构

Structure of the capsular polysaccharide of Actinobacillus pleuropneumoniae serotype 5b.

作者信息

Altman E, Brisson J R, Gagné S M, Perry M B

机构信息

Institute for Biological Sciences, National Research Council of Canada, Ontario.

出版信息

Eur J Biochem. 1992 Feb 15;204(1):225-30. doi: 10.1111/j.1432-1033.1992.tb16628.x.

Abstract

The capsular polysaccharide of Actinobacillus pleuropneumoniae serotype 5b (strain L20) was found to be a high molecular mass polymer composed of 2-acetamido-2-deoxy-D-glucose, D-glucose, and 3-deoxy-D-manno-octulosonic acid (KDO). Methylation analysis, partial hydrolysis and a combination of homonuclear and 1H-detected heteronuclear shift-correlated nuclear magnetic resonance experiments showed the polysaccharide to be a branched polymer of a trisaccharide repeating unit, having the structure: [formula; see text]

摘要

胸膜肺炎放线杆菌5b型(菌株L20)的荚膜多糖被发现是一种高分子量聚合物,由2-乙酰氨基-2-脱氧-D-葡萄糖、D-葡萄糖和3-脱氧-D-甘露糖辛酸(KDO)组成。甲基化分析、部分水解以及同核和1H检测的异核位移相关核磁共振实验相结合表明,该多糖是一种三糖重复单元的支链聚合物,其结构为:[化学式;见原文]

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