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胸膜肺炎放线杆菌7型荚膜多糖的结构

Structure of the capsular polysaccharide from Actinobacillus pleuropneumoniae serotype 7.

作者信息

Beynon L M, Perry M B, Richards J C

机构信息

Division of Biological Sciences, National Research Council of Canada, Ottawa, Ontario.

出版信息

Carbohydr Res. 1991 Jan 15;209:211-23. doi: 10.1016/0008-6215(91)80158-j.

Abstract

The structure of the capsular polysaccharide antigen of A. pleuropneumoniae serotype 7 was determined using 1D- and 2D-n.m.r. methods. Dephosphorylation, methylation, and g.l.c.-mass spectrometry methods were used to confirm the analysis. The type-7 specific polysaccharide was a high-molecular-weight teichoic acid-type polymer of D-galactose, glycerol, and phosphate (2:1:1), composed of glycosylglycerol repeating units joined through monophosphate diester linkages and with the structure: [formula: see text]

摘要

利用一维和二维核磁共振方法确定了胸膜肺炎放线杆菌7型荚膜多糖抗原的结构。采用去磷酸化、甲基化和气相色谱-质谱法对分析结果进行确认。7型特异性多糖是一种由D-半乳糖、甘油和磷酸盐(2:1:1)组成的高分子量磷壁酸型聚合物,由通过单磷酸二酯键连接的糖基甘油重复单元组成,其结构为:[化学式:见原文]

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