Department of Pharmaceutics, Banaras Hindu University, Varanasi-5.
Planta Med. 1981 Jul;42(7):279-83. doi: 10.1055/s-2007-971641.
A new triterpenoid saponin, named justicisaponin-I, has been isolated from Justicia simplex D. Don. (Acanthaceae). It has been assigned oleanolic acid-3-O-beta-D-glucopyranosyl-4'-O-ferulate structure (1) on the basis of chemical transformation and comprehensive spectral evidence. Justicisaponin-I has produced significant sperm acrosomal membrane stabilizing action and may prove to be a potent antifertility agent.
一种新的三萜皂苷,命名为绞股蓝皂苷-I,已从绞股蓝(爵床科)中分离得到。根据化学转化和综合光谱证据,它被分配为齐墩果酸-3-O-β-D-吡喃葡萄糖基-4'-O-阿魏酸结构(1)。绞股蓝皂苷-I 对精子顶体膜具有显著的稳定作用,可能是一种有效的抗生育剂。