肥皂草皂苷C，首个含α-D-半乳糖的三萜皂苷，以及来自肥皂草的五种相关化合物。
Saponarioside C, the first alpha-D-galactose containing triterpenoid saponin, and five related compounds from Saponaria officinalis.
作者信息
Jia Z, Koike K, Nikaido T
机构信息
Department of Pharmacognosy, School of Pharmaceutical Sciences, Toho University 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
出版信息
J Nat Prod. 1999 Mar;62(3):449-53. doi: 10.1021/np980434w.
Six novel triterpenoid saponins, named saponariosides C-H, were isolated from the whole plants of Saponaria officinalis. Their structures were established as saponarioside C (1), 3-O-beta-D-xylopyranosyl-gypsogenic acid-28-O-alpha-D-galactopyranosyl-(1-->6)-beta-D-glucopyranosyl-(1-- >6)-[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranoside; saponarioside D (2), 3-O-beta-D-xylopyranosyl-gypsogenic acid-28-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->6) -[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranoside; saponarioside E (3), 3-O-beta-D-glucopyranosyl-gypsogenic acid-28-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->6) -[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranoside; saponarioside F (4), 3-O-beta-D-xylopyranosyl-16alpha-hydroxygypsogenic acid-28-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->6) -[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranoside; saponarioside G (5), 3-O-beta-D-xylopyranosyl-16alpha-hydroxygypsogenic acid-28-O-beta-D-glucopyranosyl-(1-->6)-[beta-D-glucopyranosyl-(1-->3 )]-beta-D-glucopyranoside; and saponarioside H (6), 3-O-beta-D-xylopyranosyl-gypsogenic acid-28-O-beta-D-glucopyranoside, by a combination of extensive NMR (DEPT, COSY, HOHAHA, HETCOR, HMBC, and NOESY) studies and chemical degradation.
从肥皂草的全株中分离出六种新型三萜皂苷，命名为肥皂草皂苷C - H。通过广泛的核磁共振（DEPT、COSY、HOHAHA、HETCOR、HMBC和NOESY）研究与化学降解相结合的方法，确定了它们的结构，分别为肥皂草皂苷C（1），3 - O - β - D - 吡喃木糖基 - 丝石竹皂苷元 - 28 - O - α - D - 吡喃半乳糖基 -（1→6）- β - D - 吡喃葡萄糖基 -（1→6）-[β - D - 吡喃葡萄糖基 -（1→3）]- β - D - 吡喃葡萄糖苷；肥皂草皂苷D（2），3 - O - β - D - 吡喃木糖基 - 丝石竹皂苷元 - 28 - O - β - D - 吡喃葡萄糖基 -（1→2）- β - D - 吡喃葡萄糖基 -（1→6） -[β - D - 吡喃葡萄糖基 -（1→3）]- β - D - 吡喃葡萄糖苷；肥皂草皂苷E（3），3 - O - β - D - 吡喃葡萄糖基 - 丝石竹皂苷元 - 28 - O - β - D - 吡喃葡萄糖基 -（1→2）- β - D - 吡喃葡萄糖基 -（1→6） -[β - D - 吡喃葡萄糖基 -（1→3）]- β - D - 吡喃葡萄糖苷；肥皂草皂苷F（4），3 - O - β - D - 吡喃木糖基 - 16α - 羟基丝石竹皂苷元 - 28 - O - β - D - 吡喃葡萄糖基 -（1→2）- β - D - 吡喃葡萄糖基 -（1→6） -[β - D - 吡喃葡萄糖基 -（1→3）]- β - D - 吡喃葡萄糖苷；肥皂草皂苷G（5），3 - O - β - D - 吡喃木糖基 - 16α - 羟基丝石竹皂苷元 - 28 - O - β - D - 吡喃葡萄糖基 -（1→6）-[β - D - 吡喃葡萄糖基 -（1→3 ）]- β - D - 吡喃葡萄糖苷；以及肥皂草皂苷H（6），3 - O - β - D - 吡喃木糖基 - 丝石竹皂苷元 - 28 - O - β - D - 吡喃葡萄糖苷。
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