De Cauwer Harald, Bogers John-Paul, Duwel Valerie, den Hauwe Van, Croese Peter, Van Marck Eric
Department of Neurology, Klina Regional Hospital, Augustijnslei 100, 2930, Brasschaat, Belgium.
J Neurol. 2007 Aug;254(8):1009-11. doi: 10.1007/s00415-006-0469-4. Epub 2007 Apr 3.
We report the second case of a cerebral intraparenchymatous malignant nerve sheath tumor, triton tumor variant. It is the first case associated with neurofibromatosis reported in literature thus far. The therapy of these aggressive tumors is rather disappointing as recurrence of the tumor despite complete surgical resection and even adjuvant radiotherapy and/or chemotherapy is seen in most patients. It is still unknown if survival is influenced by tumor localization, size or malignancy grade. In this case therapy also proved to be unsuccessful.
我们报告了第二例脑实质内恶性神经鞘瘤，即蝾螈瘤变体。这是迄今为止文献中报道的首例与神经纤维瘤病相关的病例。这些侵袭性肿瘤的治疗相当令人失望，因为大多数患者尽管进行了完整的手术切除，甚至辅助放疗和/或化疗，仍会出现肿瘤复发。目前尚不清楚生存是否受肿瘤位置、大小或恶性程度的影响。在该病例中，治疗也被证明是不成功的。
