Cai Jia, Li Fan, Zhou Wei, Luo He-Sheng
Department of Gastroenterology, Renmin Hospital, Wuhan University, Jie Fang Road 238, Wuchang 430060, Wuhan, P R China.
Dig Dis Sci. 2007 Nov;52(11):3169-73. doi: 10.1007/s10620-006-9548-8. Epub 2007 Apr 3.
Diseases of the ileocecal junction are mostly ulcerative. The aim of this study was to investigate the value of colonoscopy on the diagnosis of the causes of ileocecal ulcer. Clinical manifestations, diagnosis, and endoscopic and histopathologic features of 52 hospitalized cases of ileocecal ulcer were retrospectively analyzed. In this study, the causes of ileocecal ulcer were intestinal tuberculosis (32.7%), Crohn's disease (19.2%), carcinoma of the cecum (17.3%), ulcerative colitis (UC; 13.5%), solitary ulcer of the colon (9.6%), lymphoma (5.8%), and leiomyoma (1.9%). The concordance rate of diagnosis at endoscopy to final diagnosis was 78.8%; the rate of endoscopic misdiagnosis was 21.2%. The concordance rate of clinical diagnosis before colonoscopy to the final diagnosis was 17.3%. Colonoscopy plays an important role in the diagnosis of the diseases that lead to ileocecal ulcer. However, colonoscopy may cause some erroneous diagnosis. To attain the correct diagnosis, endoscopic features, pathologic results, and the other clinical data should be analyzed together.
