Abdullah Kawsari, Malek Mohammad A, Faruque Abu S G, Salam Mohammed A, Ahmed T
Clinical Sciences Division, International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka, Bangladesh.
Acta Paediatr. 2007 Mar;96(3):396-400. doi: 10.1111/j.1651-2227.2007.00117.x.
The study aimed at assessing clinical and nutritional features and socioeconomic characteristics of the first birth-order children (1-48 months) of adolescent mothers.
Five hundred and thirty-nine first birth-order children of both sexes, aged 1-48 month(s) were studied. All study children had adolescent mothers aged < or =19 years (when attending hospital), who attended (as a patient) the Dhaka hospital of ICDDR, B during 2000-2005. A similar group of children (n = 540) of mothers aged 25-29 years (when attending hospital) constituted the comparison group.
Malnutrition indicated by underweight [OR 2.3, 95% CI 1.7-3.1, p < 0.001], stunting [OR 2.1, 95% CI 1.5-2.8, p < 0.001], wasting [OR 1.8, 95% CI 1.3-2.7, p = 0.001], infancy (<12 months old) [OR 2.8, 95% CI 2.1-3.9, p < 0.001], duration of hospitalization (> or =48 h) [OR 1.6, 95% CI 1.2-2.2, p = 0.001], DPT immunization [OR 1.8, 95% CI 1.3-2.5, p = 0.001] and maternal illiteracy (no formal schooling) [OR 1.5, 95% CI 1.1-2.0, p = 0.007] were significantly associated with children of adolescent mothers, after adjusting for co-variates in the logistic regression analysis. Similar results were also observed when different indices of malnutrition (stunting, underweight or wasting) were added separately to the different models.
Children of adolescent mothers are likely to be more malnourished, have lesser opportunities for DPT immunization and have longer duration of hospitalization. Adolescent mothers were also more likely to be illiterate. Therefore, the development of preventive and therapeutic strategies will be required to reduce morbidity and improve the health and nutrition status of both children and their adolescent mothers.
本研究旨在评估青春期母亲的头胎子女(1至48个月)的临床、营养特征及社会经济特征。
对539名年龄在1至48个月的头胎子女(男女均有)进行了研究。所有研究对象的母亲在就诊时年龄小于或等于19岁,她们于2000年至2005年期间在孟加拉国腹泻疾病研究国际中心达卡医院就诊。另一组由母亲年龄在25至29岁(就诊时)的儿童(n = 540)构成对照组。
在逻辑回归分析中对协变量进行校正后,青春期母亲的子女出现营养不良(以体重不足表示)[比值比(OR)2.3,95%可信区间(CI)1.7 - 3.1,p < 0.001]、发育迟缓[OR 2.1,95% CI 1.5 - 2.8,p < 0.001]、消瘦[OR 1.8,95% CI 1.3 - 2.7,p = 0.001]、婴儿期(<12个月)[OR 2.8,95% CI 2.1 - 3.9,p < 0.001]、住院时间(≥48小时)[OR 1.6,95% CI 1.2 - 2.2,p = 0.001]、白喉-百日咳-破伤风(DPT)疫苗接种[OR 1.8,95% CI 1.3 - 2.5,p = 0.001]以及母亲文盲(未接受过正规教育)[OR 1.5,95% CI 1.1 - 2.0,p = 0.007]的情况均与青春期母亲的子女显著相关。当分别将不同的营养不良指标(发育迟缓、体重不足或消瘦)添加到不同模型中时,也观察到了类似结果。
青春期母亲的子女更易出现营养不良,接受DPT疫苗接种的机会较少,住院时间更长。青春期母亲也更可能是文盲。因此,需要制定预防和治疗策略以降低发病率,并改善儿童及其青春期母亲的健康和营养状况。