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1
Partial amino-acid sequence of NAD-specific glutamate dehydrogenase of Neurospora crassa.粗糙脉孢菌NAD特异性谷氨酸脱氢酶的部分氨基酸序列
Proc Natl Acad Sci U S A. 1975 Dec;72(12):4891-4. doi: 10.1073/pnas.72.12.4891.
2
Amino-acid sequence of NADP-specific glutamate dehydrogenase of neurospora crassa.粗糙脉孢菌NADP特异性谷氨酸脱氢酶的氨基酸序列。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4361-5. doi: 10.1073/pnas.71.11.4361.
3
The amino acid composition and some properties of the NAD + -specific glutamate dehydrogenase from Neurospora crassa.粗糙脉孢菌中NAD⁺特异性谷氨酸脱氢酶的氨基酸组成及某些特性
Biochim Biophys Acta. 1971 Oct;251(1):21-30. doi: 10.1016/0005-2795(71)90054-7.
4
The amino acid sequence of Neurospora NADP-specific glutamate dehydrogenase. The tryptic peptides.粗糙脉孢菌NADP特异性谷氨酸脱氢酶的氨基酸序列。胰蛋白酶肽段
Biochem J. 1975 Sep;149(3):739-48. doi: 10.1042/bj1490739.
5
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. IV. The COOH-terminal 669 residues of the peptide chain; comparison with other glutamate dehydrogenases.粗糙脉孢菌的烟酰胺腺嘌呤二核苷酸特异性谷氨酸脱氢酶。IV. 肽链的羧基末端669个残基；与其他谷氨酸脱氢酶的比较。
J Biol Chem. 1977 Nov 25;252(22):8142-9.
6
Secondary structure predictions for the NAD-specific glutamate dehydrogenase of Neurospora crassa.粗糙脉孢菌NAD特异性谷氨酸脱氢酶的二级结构预测
J Biol Chem. 1980 Aug 25;255(16):8001-4.
7
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora crassa. IX. Isolation and sequences of several large cyanogen bromide peptides.粗糙脉孢菌的烟酰胺腺嘌呤二核苷酸特异性谷氨酸脱氢酶。IX. 几种大的溴化氰肽段的分离与序列分析
J Biol Chem. 1977 Nov 25;252(22):8196-205.
8
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora crassa. Isolation and sequences of several cyanogen bromide peptides from the NH2-terminal portion of the peptide chain.粗糙脉孢菌的烟酰胺腺嘌呤二核苷酸特异性谷氨酸脱氢酶。肽链NH2末端部分几个溴化氰肽段的分离与序列分析。
J Biol Chem. 1980 Aug 25;255(16):7984-92.
9
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. VI. Isolation and sequences of eighteen fragments from the cyanogen bromide digest.粗糙脉孢菌的烟酰胺腺嘌呤二核苷酸特异性谷氨酸脱氢酶。VI. 溴化氰消化产物中18个片段的分离与序列分析
J Biol Chem. 1977 Nov 25;252(22):8160-73.
10
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.粗糙脉孢菌的烟酰胺腺嘌呤二核苷酸特异性谷氨酸脱氢酶。III. 含有选择性标记赖氨酸和半胱氨酸残基的肽段的分离与序列分析
J Biol Chem. 1974 Dec 25;249(24):7936-41.

本文引用的文献

1
Effect of glutamic acid on the formation of two glutamic acid dehydrogenases of Neurospora.谷氨酸对粗糙脉孢菌两种谷氨酸脱氢酶形成的影响。
Biochem Biophys Res Commun. 1962 Jan 24;6:404-9. doi: 10.1016/0006-291x(62)90364-9.
2
Concurrent regulation of glutamic acid dehydrogenases of Neurospora.粗糙脉孢菌谷氨酸脱氢酶的协同调控
Arch Biochem Biophys. 1962 Jun;97:582-8. doi: 10.1016/0003-9861(62)90127-3.
3
The occurrence of two different glutamic dehydrogenases in Neurospora.粗糙脉孢菌中两种不同谷氨酸脱氢酶的存在。
Can J Microbiol. 1961 Jun;7:319-28. doi: 10.1139/m61-039.
4
An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase.溴化氰裂解多肽链的条件研究：应用于过氧化氢酶
Arch Biochem Biophys. 1969 Mar;130(1):551-6. doi: 10.1016/0003-9861(69)90069-1.
5
Structure of alpha-1-CB8, a large cyanogen bromide produced fragment from the alpha-1 chain of rat collagen. The nature of a hydroxylamine-sensitive bond and composition of tryptic peptides.α-1-CB8的结构，一种由大鼠胶原蛋白α-1链经溴化氰裂解产生的大片段。一种对羟胺敏感的键的性质及胰蛋白酶肽段的组成。
Biochemistry. 1970 Jun 9;9(12):2408-21. doi: 10.1021/bi00814a004.
6
Sequence of bovine liver glutamate dehydrogenase. II. Sequences of tryptic peptides.牛肝谷氨酸脱氢酶的序列。II. 胰蛋白酶肽段的序列
J Biol Chem. 1971 Apr 25;246(8):2374-99.
7
Aminotripeptidase of swine kidney. I. Isolation and characterization of three different forms; utility of the enzyme in sequence work.猪肾氨基三肽酶。I. 三种不同形式的分离与特性；该酶在序列研究中的应用
J Biol Chem. 1973 Mar 10;248(5):1672-83.
8
Carboxypeptidase from yeast. Large scale preparation and the application to COOH-terminal analysis of peptides and proteins.酵母羧肽酶。大规模制备及其在肽和蛋白质羧基末端分析中的应用。
J Biol Chem. 1973 Apr 10;248(7):2296-302.
9
Staphylococcal protease: a proteolytic enzyme specific for glutamoyl bonds.葡萄球菌蛋白酶：一种对谷氨酰键具有特异性的蛋白水解酶。
Proc Natl Acad Sci U S A. 1972 Dec;69(12):3506-9. doi: 10.1073/pnas.69.12.3506.
10
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.粗糙脉孢菌的烟酰胺腺嘌呤二核苷酸特异性谷氨酸脱氢酶。III. 含有选择性标记赖氨酸和半胱氨酸残基的肽段的分离与序列分析
J Biol Chem. 1974 Dec 25;249(24):7936-41.

粗糙脉孢菌NAD特异性谷氨酸脱氢酶的部分氨基酸序列

Partial amino-acid sequence of NAD-specific glutamate dehydrogenase of Neurospora crassa.

作者信息

Austen B M, Nyc J F, Degani Y, Smith E L

出版信息

Proc Natl Acad Sci U S A. 1975 Dec;72(12):4891-4. doi: 10.1073/pnas.72.12.4891.

DOI:10.1073/pnas.72.12.4891
PMID:174080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388838/
Abstract

Parts of the primary structure of the NAD-specific glutamate dehydrogenase [L-glutamate:NAD oxidoreductase (deaminating), EC 1.4.1.2] from Neurospora crassa are presented. Segments of the sequence representing 886 unique amino-acid residues have been determined; the largest contains 267 residues. There are only short regions of possible homology between this enzyme and the glutamate dehydrogenases of bovine liver or the NADP-specific enzyme of Neurospora. The large size of the subunit (116,000 molecular weight) of the NAD-specific glutamate dehydrogenase is unusual when compared to other known dehydrogenases.

摘要

本文展示了粗糙脉孢菌中NAD特异性谷氨酸脱氢酶[L-谷氨酸：NAD氧化还原酶（脱氨基），EC 1.4.1.2]一级结构的部分内容。已确定代表886个独特氨基酸残基的序列片段；最大的片段包含267个残基。该酶与牛肝谷氨酸脱氢酶或粗糙脉孢菌的NADP特异性酶之间仅存在可能的短同源区域。与其他已知脱氢酶相比，NAD特异性谷氨酸脱氢酶的亚基（分子量116,000）尺寸较大，这很不寻常。