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一种来自酵母的核糖体依赖性GTP酶,与延伸因子2不同。

A ribosome-dependent GTPase from yeast distinct from elongation factor 2.

作者信息

Skogerson L, Wakatama E

出版信息

Proc Natl Acad Sci U S A. 1976 Jan;73(1):73-6. doi: 10.1073/pnas.73.1.73.

DOI:10.1073/pnas.73.1.73
PMID:174100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC335841/
Abstract

Three proteins required for poly(U)-directed polyphenylalanine synthesis have been separated from yeast. Two of the factors correspond to the elongation factors 1 and 2 described for other eukaryotic systems, according to the criteria of phenylalanyl-tRNA binding and diphtheria toxin-catalyzed ADP-ribosylation. The third protein, while absolutely required for polyphenylalanine synthesis, was a more active ribosome-dependent GTPase than elongation factor 2.

摘要

已从酵母中分离出聚(U)指导的聚苯丙氨酸合成所需的三种蛋白质。根据苯丙氨酰 - tRNA结合和白喉毒素催化的ADP核糖基化标准,其中两种因子对应于其他真核系统中描述的延伸因子1和2。第三种蛋白质虽然是聚苯丙氨酸合成绝对必需的,但它是一种比延伸因子2更具活性的核糖体依赖性GTP酶。

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A ribosome-dependent GTPase from yeast distinct from elongation factor 2.一种来自酵母的核糖体依赖性GTP酶,与延伸因子2不同。
Proc Natl Acad Sci U S A. 1976 Jan;73(1):73-6. doi: 10.1073/pnas.73.1.73.
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本文引用的文献

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Studies on the formation of trensfer ribonucleic acid-ribosome complexes. V. On the function of a soluble transfer factor in protein synthesis.转运核糖核酸-核糖体复合物形成的研究。V. 一种可溶性转移因子在蛋白质合成中的作用。
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Translation: its mechanism and control.翻译:其机制与控制。
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8
Protein biosynthesis.蛋白质生物合成
Annu Rev Biochem. 1971;40:409-48. doi: 10.1146/annurev.bi.40.070171.002205.
9
Formation of a ternary complex between yeast aminoacyl-tRNA binding factor, GTP, and aminoacyl-tRNA.酵母氨酰-tRNA结合因子、GTP和氨酰-tRNA之间三元复合物的形成。
Biochem Biophys Res Commun. 1970 Mar 12;38(5):864-70. doi: 10.1016/0006-291x(70)90800-4.
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Stepwise synthesis of a tripeptide.三肽的逐步合成
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