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Hypothalamic PVN contributes to acute intermittent hypoxia-induced sympathetic but not phrenic long-term facilitation.下丘脑室旁核参与急性间歇性低氧诱导的交感神经但不膈神经长期易化。
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[Objective measurement of work of breathing with CPAP and BiLEVEL ventilation].[持续气道正压通气和双水平通气时呼吸功的客观测量]
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Intermittent hypoxia, respiratory plasticity and sleep apnea in humans: present knowledge and future investigations.间歇性低氧、呼吸可塑性与人类睡眠呼吸暂停：现有知识与未来研究。
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Urethane inhibits genioglossal long-term facilitation in un-paralyzed anesthetized rats.氨酯抑制未麻痹麻醉大鼠的颏舌肌长时程易化。
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本文引用的文献

1
Phrenic long-term facilitation is robust to hypercapnia and hypocapnia but not hyperventilatory hypotension under PEEP.膈神经长期易化对高碳酸血症和低碳酸血症具有较强的耐受性，但在呼气末正压通气（PEEP）情况下对过度通气性低血压不具有耐受性。
Respir Physiol Neurobiol. 2007 Aug 15;158(1):107-11. doi: 10.1016/j.resp.2007.01.017. Epub 2007 Feb 3.
2
Long-term facilitation of ventilation and genioglossus muscle activity is evident in the presence of elevated levels of carbon dioxide in awake humans.在清醒的人类中，当二氧化碳水平升高时，通气和颏舌肌活动的长期促进作用很明显。
Am J Physiol Regul Integr Comp Physiol. 2006 Oct;291(4):R1111-9. doi: 10.1152/ajpregu.00896.2005. Epub 2006 Apr 20.
3
Determinants of long-term facilitation in humans during NREM sleep.非快速眼动睡眠期间人类长期易化的决定因素。
J Appl Physiol (1985). 2003 Jan;94(1):53-9. doi: 10.1152/japplphysiol.00476.2002. Epub 2002 Sep 6.
4
Long-term facilitation of ventilation is not present during wakefulness in healthy men or women.在健康男性或女性清醒期间不存在通气的长期促进作用。
J Appl Physiol (1985). 2002 Dec;93(6):2129-36. doi: 10.1152/japplphysiol.00135.2002. Epub 2002 Aug 30.
5
Long-term facilitation in obstructive sleep apnea patients during NREM sleep.阻塞性睡眠呼吸暂停患者非快速眼动睡眠期间的长期易化作用。
J Appl Physiol (1985). 2001 Dec;91(6):2751-7. doi: 10.1152/jappl.2001.91.6.2751.
6
Apnoea characteristics across the night in severe obstructive sleep apnoea: influence of body posture.重度阻塞性睡眠呼吸暂停患者夜间的呼吸暂停特征：体位的影响
Eur Respir J. 2001 Aug;18(2):340-6. doi: 10.1183/09031936.01.00038101.
7
Ventilatory long-term facilitation in unanesthetized rats.未麻醉大鼠的通气长期易化作用
J Appl Physiol (1985). 2001 Aug;91(2):709-16. doi: 10.1152/jappl.2001.91.2.709.
8
Long-term facilitation of ventilation in humans during NREM sleep.非快速眼动睡眠期间人类通气的长期促进作用。
Sleep. 1998 Nov 1;21(7):709-16.
9
Effects of sustained and repetitive isocapnic hypoxia on ventilation and genioglossal and diaphragmatic EMGs.持续性和重复性等碳酸性低氧对通气及颏舌肌和膈肌肌电图的影响。
J Appl Physiol (1985). 1996 Aug;81(2):866-75. doi: 10.1152/jappl.1996.81.2.866.

Long-term facilitation (LTF) and obstructive sleep apnea.

作者信息

White David P

机构信息

Division of Sleep Medicine, Brigham and Women's Hospital, Sleep Research at BI, 75 Francis Street, Boston, MA 02115, United States.

出版信息

Respir Physiol Neurobiol. 2007 Aug 15;158(1):112-3. doi: 10.1016/j.resp.2007.03.001. Epub 2007 Mar 12.

DOI:10.1016/j.resp.2007.03.001
PMID:17412653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4287365/
Abstract
摘要