Sri-Ram Kesavan, Vellodi Ashok, Pitt Matthew, Eastwood Deborah M
Department of Orthopaedics, Great Ormond Street Hospital for Children, London, UK.
J Pediatr Orthop B. 2007 May;16(3):225-8. doi: 10.1097/BPB.0b013e328016830b.
Thirty-two patients (61 limbs) with lysosomal storage disorders underwent surgery for 'carpal tunnel syndrome'. Twenty-two limbs underwent a simple decompression whereas 39 limbs underwent additional neurolysis and tenosynovectomy. Data were incomplete for six patients (12 limbs). The mean age at operation for the decompression group (11 patients) was 10.5 years and for the neurolysis group (15 patients), 6.9 years. Overall, using a neurophysiological rating system, 39% of limbs demonstrated sensory improvement and 47% motor improvement with no significant difference between the groups. Only in the neurolysis group was a decline in motor conduction (2/29 limbs) or sensory conduction (four limbs) noted. Using neurophysiological criteria, no added benefit from external neurolysis was identified.
32例（61条肢体）溶酶体贮积症患者接受了“腕管综合征”手术。22条肢体接受了单纯减压，39条肢体接受了额外的神经松解和腱鞘切除术。6例患者（12条肢体）的数据不完整。减压组（11例患者）的平均手术年龄为10.5岁，神经松解组（15例患者）为6.9岁。总体而言，使用神经生理学评分系统，39%的肢体感觉改善，47%的肢体运动改善，两组之间无显著差异。仅在神经松解组中，观察到运动传导（2/29条肢体）或感觉传导（4条肢体）下降。根据神经生理学标准，未发现外部神经松解有额外益处。
