Le Scodan Romuald, Wyplosz Benjamin, Couchon Sophie, Housset Martin, Laccourreye Ollivier
Department of Radiation Oncology, Université Paris V-René Descartes, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.
Eur Arch Otorhinolaryngol. 2007 Sep;264(9):1099-102. doi: 10.1007/s00405-007-0298-9. Epub 2007 Apr 6.
This case report documents a UV-light-induced recall phenomenon and reviews the medical literature. In this patient, we observed a severe recall phenomenon precipitated by an extensive sunlight exposure after a chemoradiotherapy organ preservation protocol. Radiation recall phenomenon is a rare but well-described phenomenon, without clear radiation or drug-specific characteristics. In the medical literature, radiation recall following UV-sunlight exposure seems to be an exceptional event. The etiology remains unknown but could involve local hypersensitivity through a non-immune activation of inflammatory pathways. Due to the increasing number of patients with head and neck malignancies managed with induction chemotherapy and/or chemoradiation organ preservation protocols, the otorhinolaryngologist--head and neck surgeons as well as the radiation therapist should become aware and familiar with this phenomenon.
本病例报告记录了紫外线诱导的回忆现象，并对医学文献进行了综述。在该患者中，我们观察到在放化疗器官保留方案后，因大量阳光照射引发了严重的回忆现象。放射回忆现象虽罕见但已有充分描述，无明确的放射或药物特异性特征。在医学文献中，紫外线照射后的放射回忆似乎是一个特殊事件。其病因尚不清楚，但可能通过炎症途径的非免疫激活涉及局部超敏反应。由于采用诱导化疗和/或放化疗器官保留方案治疗的头颈部恶性肿瘤患者数量不断增加，耳鼻喉科头颈外科医生以及放射治疗师应了解并熟悉这一现象。
