丙二醛和超氧化物歧化酶在白内障形成中的作用。

Role of malondialdehyde and superoxide dismutase in cataractogenesis.

作者信息

Bhatia R P, Rai Ruchi, Rao G R K

机构信息

Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

出版信息

Ann Ophthalmol (Skokie). 2006 Summer;38(2):103-6. doi: 10.1385/ao:38:2:103.

DOI:10.1385/ao:38:2:103

PMID:17416937

Abstract

Malondialdehyde (MDA) and superoxide dismutase (SOD) in lens and plasma of patients with age-related and myopic cataract were assessed. Higher levels of lens MDA in myopic patients showed a greater lipid peroxidation process than in patients with age-related cataract indicating higher oxidative stress in myopic lens. The difference in plasma MDA of myopic cataract and age-related cataract patients was not significant. The SOD level was lower in myopic patients than in patients with age-related cataract.

摘要

对年龄相关性白内障和近视性白内障患者晶状体及血浆中的丙二醛（MDA）和超氧化物歧化酶（SOD）进行了评估。近视患者晶状体中较高水平的MDA表明其脂质过氧化过程比年龄相关性白内障患者更严重，提示近视晶状体的氧化应激更高。近视性白内障患者和年龄相关性白内障患者血浆MDA的差异不显著。近视患者的SOD水平低于年龄相关性白内障患者。