Kutluay Ekrem, Pakoz Burak, Yuksel Alper, Beydoun Ahmad
Department of Neurology, Kent Hospital, Izmir, Turkey.
Epilepsy Behav. 2007 Jun;10(4):626-8. doi: 10.1016/j.yebeh.2007.03.001. Epub 2007 Apr 5.
Pure alexia is a rare disorder usually caused by an ischemic or hemorrhagic stroke. We describe a case of pure alexia due to nonconvulsive status epilepticus (NCSE). This 57-year-old man presented in a hyperosmolar, nonketotic state with fluctuations in mental status and an inability to read. His EEG was diagnostic of NCSE originating from the left temporo-occipital region. MRI of the brain revealed increased FLAIR signal over the left occipitotemporal region. Following initiation of antiepileptic treatment, his neurological examination normalized concomitantly with resolution of the NCSE. A follow-up MRI scan of the brain obtained 1 month later was normal. NCSE can have unusual clinical manifestations, and a high index of suspicion is necessary to correctly diagnose these patients.
纯失读症是一种罕见的疾病，通常由缺血性或出血性中风引起。我们描述了一例由非惊厥性癫痫持续状态（NCSE）导致的纯失读症病例。这名57岁男性以高渗性、非酮症状态就诊，伴有精神状态波动和无法阅读的症状。他的脑电图诊断为起源于左侧颞枕区的NCSE。脑部MRI显示左侧枕颞区FLAIR信号增强。在开始抗癫痫治疗后，他的神经系统检查恢复正常，同时NCSE也得到缓解。1个月后进行的脑部随访MRI扫描结果正常。NCSE可能有不寻常的临床表现，对这些患者进行正确诊断需要高度的怀疑指数。
